Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
about
Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk.Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor functionA quantitative protein interaction network for the ErbB receptors using protein microarraysA Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding.Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signalingCell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval developmentEndosomal localization and function of sorting nexin 1Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.Human VPS34 is required for internal vesicle formation within multivesicular endosomesUbc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradationSCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complexSpatial regulation of epidermal growth factor receptor signaling by endocytosisProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesFunctional deregulation of KIT: link to mast cell proliferative diseases and other neoplasmsMolecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agentsP130Cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylationEGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell LineH-Ras signaling and K-Ras signaling are differentially dependent on endocytosis.PrPC directly interacts with proteins involved in signaling pathwaysc-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation.Vinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface.Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre.Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells.Cholesterol dictates the freedom of EGF receptors and HER2 in the plane of the membranePolarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors.Signaling components of redox active endosomes: the redoxosomes.The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recyclingCell surface receptors for signal transduction and ligand transport: a design principles study.A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin.CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR.β-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt.Endoplasmic reticulum-localized human papillomavirus type 16 E5 protein alters endosomal pH but not trans-Golgi pH.Dynamic imaging of molecular assemblies in live cells based on nanoparticle plasmon resonance coupling.The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine modeKinetic modeling of biological systems.A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.A novel TIP30 protein complex regulates EGF receptor signaling and endocytic degradation.
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P2860
Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2001
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of epidermal growth ...... and intracellular trafficking
@en
Regulation of epidermal growth ...... and intracellular trafficking.
@nl
type
label
Regulation of epidermal growth ...... and intracellular trafficking
@en
Regulation of epidermal growth ...... and intracellular trafficking.
@nl
prefLabel
Regulation of epidermal growth ...... and intracellular trafficking
@en
Regulation of epidermal growth ...... and intracellular trafficking.
@nl
P2093
P2860
P356
P1476
Regulation of epidermal growth ...... and intracellular trafficking
@en
P2093
P2860
P304
P356
10.1091/MBC.12.6.1897
P577
2001-06-01T00:00:00Z