Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
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Biopersistence and brain translocation of aluminum adjuvants of vaccinesAlum: an old dog with new tricksMolecular mechanisms regulating NLRP3 inflammasome activationCathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug CandidateAging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicansActivation of NLRP3 inflammasome by crystalline structures via cell surface contact.The avian influenza vaccine Emerflu. Why did it fail?A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.Multi-parametric analysis of cell death pathways using live-cell microscopy.Fluorescent nanodiamonds as a relevant tag for the assessment of alum adjuvant particle biodispositionAdjuvants in the Driver's Seat: How Magnitude, Type, Fine Specificity and Longevity of Immune Responses Are Driven by Distinct Classes of Immune PotentiatorsDistinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents.Comparative Safety of Vaccine Adjuvants: A Summary of Current Evidence and Future NeedsNLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx.Monosodium urate crystal-induced pro-interleukin-1β production is post-transcriptionally regulated via the p38 signaling pathway in human monocytes.Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearanceLysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21.Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.High-density lipoprotein reduces inflammation from cholesterol crystals by inhibiting inflammasome activation.Soluble Uric Acid Activates the NLRP3 Inflammasome.Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophagesOld and new adjuvants.On the road to inflammation: linking lysosome disruption, lysosomal protease release and necrotic death of immune cellsBlood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammationMultiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β ActivationComplete lysosomal disruption: a route to necrosis, not to the inflammasome.Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists.A high concentration of DMSO activates caspase-1 by increasing the cell membrane permeability of potassium.Alum Activates the Bovine NLRP3 Inflammasome.Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat.Dousing fire with gasoline: interplay between lysosome damage and the NLRP3 inflammasome. Focus on "NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and CaAlarmins and immunity.Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System.Dysfunction of various organelles provokes multiple cell death after quantum dot exposure.Systematic Overview of Solid Particles and Their Host Responses.Lysosomal membrane permeabilization causes secretion of IL-1β in human vascular smooth muscle cellsHigh-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis
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Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@en
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@nl
type
label
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@en
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@nl
prefLabel
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@en
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@nl
P2093
P2860
P356
P1433
P1476
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.
@en
P2093
Felipe Diaz-Griffero
Heriberto Lima
Jürgen Brojatsch
Kartik Chandran
Lee S Jacobson
Michael F Goldberg
P2860
P304
P356
10.4161/CC.24903
P577
2013-05-20T00:00:00Z