Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants.
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Explosive genetic evidence for explosive human population growthUnderstanding rare and common diseases in the context of human evolutionInference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples.A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets.Incomplete dominance of deleterious alleles contributes substantially to trait variation and heterosis in maize.The impact of rare variation on gene expression across tissues.Evidence of directional and stabilizing selection in contemporary humans.Genomic history of the Sardinian populationGenome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
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Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 May 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Selection and explosive growth ...... ction of causal rare variants.
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Selection and explosive growth ...... ction of causal rare variants.
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type
label
Selection and explosive growth ...... ction of causal rare variants.
@en
Selection and explosive growth ...... ction of causal rare variants.
@nl
prefLabel
Selection and explosive growth ...... ction of causal rare variants.
@en
Selection and explosive growth ...... ction of causal rare variants.
@nl
P2860
P50
P356
P1433
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Selection and explosive growth ...... ction of causal rare variants.
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P2093
John S Witte
Noah A Zaitlen
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P304
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10.1101/GR.202440.115
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2016-05-18T00:00:00Z