Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity
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Regulation of TGF-β Signal TransductionMembrane cholesterol regulates lysosome-plasma membrane fusion events and modulates Trypanosoma cruzi invasion of host cellsPalmitoylation regulates epidermal homeostasis and hair follicle differentiationSingle-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization.Pancreatic cancer circulating tumour cells express a cell motility gene signature that predicts survival after surgery.Lipid rafts play an important role for maintenance of embryonic stem cell self-renewal.Dynamics of TGF-β/Smad signalingRole of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells.FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.Disabled-2 downregulation promotes epithelial-to-mesenchymal transitionDifferential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signalingInvolvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells.Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomesShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.Regulation of TGF-β receptor activityReceptor-transporting protein 1 short (RTP1S) mediates translocation and activation of odorant receptors by acting through multiple stepsThe TGFβ receptor-interacting protein km23-1/DYNLRB1 plays an adaptor role in TGFβ1 autoinduction via its association with Ras.PICK1 promotes caveolin-dependent degradation of TGF-β type I receptor.Lysophosphatidic acid promotes cell migration through STIM1- and Orai1-mediated Ca2+(i) mobilization and NFAT2 activation.A dynein motor attachment complex regulates TGFß/Smad3 signaling.The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.Informatics approaches to understanding TGFbeta pathway regulation.Fucose-containing fraction of Ling-Zhi enhances lipid rafts-dependent ubiquitination of TGFβ receptor degradation and attenuates breast cancer tumorigenesisSmad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling.Post-translational regulation of TGF-β receptor and Smad signaling.The role of endocytic pathways in TGF-β signaling.Caveolin and TGF-β entanglements.Lipid rafts in immune signalling: current progress and future perspective.Direct regulation of transforming growth factor β-induced epithelial-mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells.TGF-β Signaling from Receptors to Smads.TGFβ1 rapidly activates Src through a non-canonical redox signaling mechanism.Primary Cilia and Coordination of Receptor Tyrosine Kinase (RTK) and Transforming Growth Factor β (TGF-β) Signaling.Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells.Coated pit-mediated endocytosis of the type I transforming growth factor-β (TGF-β) receptor depends on a di-leucine family signal and is not required for signaling.PAI-1 mediates the TGF-beta1+EGF-induced "scatter" response in transformed human keratinocytes.Cholesterol efflux stimulates metalloproteinase-mediated cleavage of occludin and release of extracellular membrane particles containing its C-terminal fragmentsCholesterol depletion in cell membranes of human airway epithelial cells suppresses MUC5AC gene expression.SMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors.New Insights into the Mechanism of Action of Soluble Klotho.Mechanistic insight into contextual TGF-β signaling.
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Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Specific activation of mitogen ...... for epithelial cell plasticity
@en
Specific activation of mitogen ...... or epithelial cell plasticity.
@nl
type
label
Specific activation of mitogen ...... for epithelial cell plasticity
@en
Specific activation of mitogen ...... or epithelial cell plasticity.
@nl
prefLabel
Specific activation of mitogen ...... for epithelial cell plasticity
@en
Specific activation of mitogen ...... or epithelial cell plasticity.
@nl
P2860
P356
P1476
Specific activation of mitogen ...... for epithelial cell plasticity
@en
P2093
Ye-Guang Chen
P2860
P304
P356
10.1091/MBC.E08-09-0898
P577
2008-12-03T00:00:00Z