2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.
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Re-replication of a centromere induces chromosomal instability and aneuploidyA Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration.Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal.Mechanisms and consequences of aneuploidy and chromosome instability in the aging brainFoci of Entotic Nuclei in Different Grades of Noninherited Renal Cell Cancers.The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.Clinical application of DNA ploidy to cervical cancer screening: A review.Implications of targeted genomic disruption of β-catenin in BxPC-3 pancreatic adenocarcinoma cells.Effect of EGFR and p-AKT Overexpression on Chromosomal Instability in Gastric Cancer.Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replicationCancer karyotypes: survival of the fittestNegative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation.A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosisThe Consequences of Chromosome Segregation Errors in Mitosis and Meiosis.Establishment of proliferative tetraploid cells from telomerase-immortalized normal human fibroblasts.Cancerous inhibitor of protein phosphatase 2A promotes premature chromosome segregation and aneuploidy in prostate cancer cells through association with shugoshin.Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.Mining the Dynamic Genome: A Method for Identifying Multiple Disease Signatures Using Quantitative RNA Expression Analysis of a Single Blood Sample.Is aneuploidy deciding your fate?Mad1 at the Golgi apparatus: a story beyond kinetochores.c-MYC-induced genomic instability.Tuning Chromosomal Instability to Optimize Tumor Fitness.Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death.Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division.Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effectsTetraploidy in cancer and its possible link to aging
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2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 13 February 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@en
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@nl
type
label
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@en
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@nl
prefLabel
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@en
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@nl
P2093
P2860
P1476
2n or not 2n: Aneuploidy, poly ...... ty in primary and tumor cells.
@en
P2093
Beth A Weaver
Eric M C Britigan
Lauren M Zasadil
P2860
P304
P356
10.1016/J.SEMCDB.2013.02.001
P577
2013-02-13T00:00:00Z