Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.
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Inflammation Shapes Stem Cells and Stemness during Infection and BeyondLoss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γMolecular and genetic alterations associated with therapy resistance and relapse of acute myeloid leukemia.Biology and relevance of human acute myeloid leukemia stem cells.Rejuvenation of aged hematopoietic stem cells.Regulation of normal and leukemic stem cells through cytokine signaling and the microenvironment.Metabolic regulation of hematopoietic and leukemic stem/progenitor cells under homeostatic and stress conditions.Metabolic Plasticity of Stem Cells and Macrophages in Cancer.Immunotherapeutic Concepts to Target Acute Myeloid Leukemia: Focusing on the Role of Monoclonal Antibodies, Hypomethylating Agents and the Leukemic Microenvironment.Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.Influence of body mass index on incidence and prognosis of acute myeloid leukemia and acute promyelocytic leukemia: A meta-analysis.Targeting the leukemic bone marrow microenvironment.A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion.Single-cell whole exome and targeted sequencing in NPM1/FLT3 positive pediatric acute myeloid leukemia.Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche.MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.Clinical implications of bone marrow adiposity."Nutrient-sensing" and self-renewal: O-GlcNAc in a new role.Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer.Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors.Adipocytes impair efficacy of antiretroviral therapy.CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting.VEGF signaling in acute leukemia: mitochondrial connections.Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy.Therapeutic Antibodies for Myeloid Neoplasms-Current Developments and Future Directions.Emerging role of lipid metabolism alterations in Cancer stem cells.Bone Marrow Adipocyte: An Intimate Partner With Tumor Cells in Bone Metastasis.The contributions of cancer cell metabolism to metastasisThe Ins and Outs of Autophagy and Metabolism in Hematopoietic and Leukemic Stem Cells: Food for ThoughtEpigenetic-Transcriptional Regulation of Fatty Acid Metabolism and Its Alterations in LeukaemiaS100 Proteins in Acute Myeloid LeukemiaMetabolic Plasticity of Tumor Cell Mitochondria
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Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
@en
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
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type
label
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
@en
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
@nl
prefLabel
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
@en
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
@nl
P2093
P2860
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P1433
P1476
Leukemic Stem Cells Evade Chem ...... on to an Adipose Tissue Niche.
@en
P2093
Alec W Stranahan
Biniam Adane
Brett Stevens
Carolien M Woolthuis
Christopher Y Park
Craig T Jordan
Dwight J Klemm
Marlene Balys
Maura Gasparetto
P2860
P356
10.1016/J.STEM.2016.06.001
P407
P577
2016-06-29T00:00:00Z