about
ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancersFBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascadeIdentification of PTPsigma as an autophagic phosphatase.Protein tyrosine phosphatases as potential therapeutic targets.A global view of the oncogenic landscape in nasopharyngeal carcinoma: an integrated analysis at the genetic and expression levels.Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric virus-cell mRNAs similar to those found in cervical cancers.PTPL1/PTPN13 regulates breast cancer cell aggressiveness through direct inactivation of Src kinaseEphrinB1: novel microtubule associated protein whose expression affects taxane sensitivityPeptide Binding to a PDZ Domain by Electrostatic Steering via Nonnative Salt Bridges.5-Azacitidine induces demethylation of PTPL1 and inhibits growth in non-Hodgkin lymphoma.Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1.Protein tyrosine phosphatases in glioma biologyPTPN13/PTPL1: an important regulator of tumor aggressiveness.Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.Tumour-suppressive role of PTPN13 in hepatocellular carcinoma and its clinical significance.PTPL1 and PKCδ contribute to proapoptotic signalling in prostate cancer cells.A missense methionine mutation augments catalytic activity but reduces thermal stability in two protein tyrosine phosphatases.Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathwaySilencing of ErbB3/ErbB2 signaling by immunoglobulin-like Necl-2.Interaction of Necl-4/CADM4 with ErbB3 and integrin α6 β4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly.miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling.High PTPN13 expression in high grade serous ovarian carcinoma is associated with a better patient outcome.The phosphatase PTPL1 is required for PTEN-mediated regulation of apical membrane size.
P2860
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P2860
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
PTPL1: a large phosphatase with a split personality.
@en
PTPL1: a large phosphatase with a split personality.
@nl
type
label
PTPL1: a large phosphatase with a split personality.
@en
PTPL1: a large phosphatase with a split personality.
@nl
prefLabel
PTPL1: a large phosphatase with a split personality.
@en
PTPL1: a large phosphatase with a split personality.
@nl
P2860
P1476
PTPL1: a large phosphatase with a split personality.
@en
P2093
Jeffrey A Toretsky
Ogan D Abaan
P2860
P2888
P304
P356
10.1007/S10555-008-9114-2
P577
2008-06-01T00:00:00Z