Bone morphogenetic protein-7 and connective tissue growth factor: novel targets for treatment of renal fibrosis?
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Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathyA Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future PerspectivesComparative genomics identifies the mouse Bmp3 promoter and an upstream evolutionary conserved region (ECR) in mammalsVEGF ameliorates tubulointerstitial fibrosis in unilateral ureteral obstruction mice via inhibition of epithelial-mesenchymal transitionExtracellular matrix molecules: potential targets in pharmacotherapy.Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosisFrequency of TGF- β and IFN- γ genotype as risk factors for acute kidney injury and death in intensive care unit patientsCysteine-rich protein 61 plays a proinflammatory role in obstructive kidney fibrosis.Circulating bone morphogenetic protein 1-3 isoform increases renal fibrosisLoss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.Loss of BMPR2 leads to high bone mass due to increased osteoblast activityEffects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy.Taming lupus-a new understanding of pathogenesis is leading to clinical advances.BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression.Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury.Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7.CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration.Transforming growth factor-β1/Smad3-independent epithelial-mesenchymal transition in type I collagen glomerulopathy.Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis.Relative Roles of TGF-β and IGFBP-5 in Idiopathic Pulmonary Fibrosis.Hypoxia interferes with connective tissue growth factor (CTGF) gene expression in human proximal tubular cell lines.BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy.BMP Signalling at the Crossroad of Liver Fibrosis and Regeneration.Bone morphogenetic protein-7 and disease progression in renal amyloidosis patients.Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys.Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy
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P2860
Bone morphogenetic protein-7 and connective tissue growth factor: novel targets for treatment of renal fibrosis?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 February 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@en
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@nl
type
label
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@en
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@nl
prefLabel
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@en
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@nl
P1476
Bone morphogenetic protein-7 a ...... r treatment of renal fibrosis?
@en
P2093
Roel Goldschmeding
P304
P356
10.1007/S11095-008-9548-9
P50
P577
2008-02-12T00:00:00Z