Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity - Wikidata - wikimedia - TriplyDB

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

http://www.wikidata.org/entity/Q37082118

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TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC myc maintains embryonic stem cell pluripotency and self-renewal Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma Transcription factor-mediated reprogramming toward hematopoietic stem cells Hymyc1 downregulation promotes stem cell proliferation in Hydra vulgaris OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis.Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state MYC on the path to cancer Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc.N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b.c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland.Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling MYC and the control of DNA replication.Growing old with Myc.Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors.Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal.The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.Signaling pathways in spermatogonial stem cells and their disruption by toxicants c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain.The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming.MYC cofactors: molecular switches controlling diverse biological outcomes.WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.Simultaneous deletion of p21Cip1/Waf1 and caspase-3 accelerates proliferation and partially rescues the differentiation defects of caspase-3 deficient hematopoietic stem cells N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.c- and N-myc regulate neural precursor cell fate, cell cycle, and metabolism to direct cerebellar development.In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.E2f1-3 are critical for myeloid development.Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic stem cells of wild type but not Id1 deficient mice.MYCN transgenic zebrafish model with the characterization of acute myeloid leukemia and altered hematopoiesis.GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells.SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells Runx transcription factors repress human and murine c-Myc expression in a DNA-binding and C-terminally dependent manner.

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Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

http://www.wikidata.org/entity/Q37082118

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

@en

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

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type

label

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

@en

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

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prefLabel

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

@en

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

@nl

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J.STEM.2008.09.005

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Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

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Anne Wilson

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Armin Ehninger

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Barbara Varnum-Finney

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H Robson MacDonald

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Irwin D Bernstein

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Isabel Ferrero

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Pei-Feng Cheng

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Robert N Eisenman

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William E Blanco-Bose

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P2860

Molecular signatures of proliferation and quiescence in hematopoietic stem cells

Myc pathways provoking cell suicide and cancer

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter

c-MYC: more than just a matter of life and death

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules

Inducible gene targeting in mice

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

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611-624

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scholarly article

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10.1016/J.STEM.2008.09.005

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6

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3

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Paul S Knoepfler

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2008-12-01T00:00:00Z

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23554739

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19041778

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2635113

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