Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses.
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HIV-1 neutralizing antibodies: understanding nature's pathwaysStructural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic PeptideInduction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States.Comparative magnitude of cross-strain conservation of HIV variable loop neutralization epitopesAnalysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies.Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primatesEvolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse modelProfiles of human serum antibody responses elicited by three leading HIV vaccines focusing on the induction of Env-specific antibodies.Antibody responses elicited through homologous or heterologous prime-boost DNA and protein vaccinations differ in functional activity and avidity.Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry.Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus.Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.Back to the future: covalent epitope-based HIV vaccine development.Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimeticStructure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine designSynergism between a CD4-mimic peptide and antibodies elicited by a constrained V3 peptide.Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma.Subtype-specific conservation of isoleucine 309 in the envelope V3 domain is linked to immune evasion in subtype C HIV-1 infection.HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate.Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies
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P2860
Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
@en
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
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type
label
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
@en
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
@nl
prefLabel
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
@en
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
@nl
P2093
P2860
P50
P1433
P1476
Soluble CD4 broadens neutraliz ...... ype B and C reference viruses.
@en
P2093
Anna Sambor
Martha C Nason
Susan Zolla-Pazner
Xueling Wu
P2860
P304
P356
10.1016/J.VIROL.2008.07.007
P407
P577
2008-09-18T00:00:00Z