Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?
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Human LPLUNC1 is a secreted product of goblet cells and minor glands of the respiratory and upper aerodigestive tractsCharacterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defenseIdentification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial culturesAdenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensingRole of epithelial mucins during airway infectionDefining the extracellular matrix using proteomicsReconstituted human upper airway epithelium as 3-d in vitro model for nasal polyposisModeling and Simulation of Mucus Flow in Human Bronchial Epithelial Cell Cultures - Part I: Idealized Axisymmetric Swirling FlowBarriers to inhaled gene therapy of obstructive lung diseases: A reviewValidation of normal human bronchial epithelial cells as a model for influenza A infections in human distal tracheaReceptor binding profiles of avian influenza virus hemagglutinin subtypes on human cells as a predictor of pandemic potential.Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation.Mucociliary interactions and mucus dynamics in ciliated human bronchial epithelial cell cultures.Continuous mucociliary transport by primary human airway epithelial cells in vitro.Airway mucus function and dysfunction.Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure.A metalloproteinase secreted by Streptococcus pneumoniae removes membrane mucin MUC16 from the epithelial glycocalyx barrierBPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung diseaseBiomarkers of Exposure to New and Emerging Tobacco and Nicotine Delivery Products.Analysis of the proteome of human airway epithelial secretionsA biophysical basis for mucus solids concentration as a candidate biomarker for airways disease.Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchi.Targeting the intracellular MUC1 C-terminal domain inhibits proliferation and estrogen receptor transcriptional activity in lung adenocarcinoma cells.Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins.Physical characterization and profiling of airway epithelial derived exosomes using light scattering.Excess Secretion of Gel-Forming Mucins and Associated Innate Defense Proteins with Defective Mucin Un-Packaging Underpin Gallbladder Mucocele Formation in Dogs.Quantitative proteomics reveals an altered cystic fibrosis in vitro bronchial epithelial secretomeMapping the protein domain structures of the respiratory mucins: a mucin proteome coverage study.CFTR, mucins, and mucus obstruction in cystic fibrosis.Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways.An engineered human conjunctival-like tissue to study ocular surface inflammatory diseases.Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airwaysReduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucinProtein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs.Changes in microRNA and mRNA expression with differentiation of human bronchial epithelial cells.The innate immune properties of airway mucosal surfaces are regulated by dynamic interactions between mucins and interacting proteins: the mucin interactome.Mass spectrometric analysis of mucin core proteins.Directional secretomes reflect polarity-specific functions in an in vitro model of human bronchial epithelium.Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung diseaseAcute toxicity testing of chemicals-Opportunities to avoid redundant testing and use alternative approaches.
P2860
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P2860
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Tracheobronchial air-liquid in ...... defense of the upper airways?
@en
Tracheobronchial air-liquid in ...... defense of the upper airways?
@nl
type
label
Tracheobronchial air-liquid in ...... defense of the upper airways?
@en
Tracheobronchial air-liquid in ...... defense of the upper airways?
@nl
prefLabel
Tracheobronchial air-liquid in ...... defense of the upper airways?
@en
Tracheobronchial air-liquid in ...... defense of the upper airways?
@nl
P2093
P2860
P1476
Tracheobronchial air-liquid in ...... defense of the upper airways?
@en
P2093
Ashley G Henderson
David Knight
Genevieve Demaria
John K Sheehan
Mehmet Kesimer
Neil E Alexis
Raymond J Pickles
Sara Kirkham
P2860
P304
P356
10.1152/AJPLUNG.90388.2008
P577
2008-10-17T00:00:00Z