Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation
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Mechanisms of ferroptosisRole of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: focusing on mitochondriaThe Stereochemistry of trans -4-Hydroxynonenal-Derived Exocyclic 1, N 2 -2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence †Conformational Interconversion of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNAFormation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductReplication Bypass of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S )-1, N 2 -Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IVFrom estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosisFormation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decompositionGeneration and biological activities of oxidized phospholipidsFormation of electrophilic oxidation products from mitochondrial cardiolipin in vitro and in vivo in the context of apoptosis and atherosclerosisThe role of one-electron reduction of lipid hydroperoxides in causing DNA damageAlpha-tocopherol is ineffective in preventing the decomposition of preformed lipid peroxides and may promote the accumulation of toxic aldehydes: a potential explanation for the failure of antioxidants to affect human atherosclerosis.Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBARedox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function.Significantly increased monounsaturated lipids relative to polyunsaturated lipids in six types of cancer microenvironment are observed by mass spectrometry imaging.ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: free radical and enzymatic oxidations.Pathological aspects of lipid peroxidation.Signaling and cytotoxic functions of 4-hydroxyalkenals.Decreased oxidative stress and greater bone anabolism in the aged, when compared to the young, murine skeleton with parathyroid hormone administration.Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress.Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome.Reactive oxygen species and dopamine receptor function in essential hypertensionThe lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysisAldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasisUnraveling the role of FoxOs in bone--insights from mouse models.Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives.A novel nonhuman primate model of cigarette smoke-induced airway diseaseRelationship of electrophilic stress to agingDouble NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient4-Hydroperoxy-2-nonenal is not just an intermediate but a reactive molecule that covalently modifies proteins to generate unique intramolecular oxidation products.Isoprostane generation and function.Isotope-coded dimethyl tagging for differential quantification of posttranslational protein carbonylation by 4-hydroxy-2-nonenal, an end-product of lipid peroxidation.Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria.Linking lipids to Alzheimer's disease: cholesterol and beyond.Degradation of Curcumin: From Mechanism to Biological ImplicationsPeptidyl-prolyl cis/trans-isomerase A1 (Pin1) is a target for modification by lipid electrophiles.Cobalt carbonyl complexes as probes for alkyne-tagged lipids.Aging mechanisms in bone.Mitochondrial aldehyde dehydrogenase-2 activation prevents β-amyloid-induced endothelial cell dysfunction and restores angiogenesis.
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Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 19 February 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation
@en
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation.
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type
label
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation
@en
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation.
@nl
prefLabel
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation
@en
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation.
@nl
P2093
P2860
P356
P1476
Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation
@en
P2093
Alan R Brash
Claus Schneider
Ned A Porter
P2860
P304
15539-15543
P356
10.1074/JBC.R800001200
P407
P577
2008-02-19T00:00:00Z