Detection and specific targeting of hypoxic regions within solid tumors: current preclinical and clinical strategies.
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The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunitiesThe relationship between tumor volume changes and serial plasma osteopontin detection during radical radiotherapy of non-small-cell lung cancer.Prognostic information of serial plasma osteopontin measurement in radiotherapy of non-small-cell lung cancerA pilot study on potential plasma hypoxia markers in the radiotherapy of non-small cell lung cancer. Osteopontin, carbonic anhydrase IX and vascular endothelial growth factor.Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients.HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression.Redox- and hypoxia-responsive MRI contrast agents.Design, synthesis and biological evaluation of 2H-benzo[b][1,4] oxazine derivatives as hypoxia targeted compounds for cancer therapeutics.Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients.Hypoxia-specific targets in cancer therapy: role of splice variantsMolecular mechanisms of hypoxia in cancer.Lipophilic 2,5-disubstituted pyrroles from the marine sponge Mycale sp. inhibit mitochondrial respiration and HIF-1 activation.Effect of a topical vasodilator on tumor hypoxia and tumor oxygen guided radiotherapy using EPR oximetryLuminal and basal-like breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism.Effects of osteopontin inhibition on radiosensitivity of MDA-MB-231 breast cancer cellsIntra- and intertumor heterogeneities in total, chronic, and acute hypoxia in xenografted squamous cell carcinomas. Detection and quantification using (immuno-)fluorescence techniques.Mapping Tumor Hypoxia In Vivo Using Pattern Recognition of Dynamic Contrast-enhanced MRI Data.Gaussian mixture model-based classification of dynamic contrast enhanced MRI data for identifying diverse tumor microenvironments: preliminary resultsMethods to study the tumor microenvironment under controlled oxygen conditions.Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1.Modulation of tumor hypoxia by topical formulations with vasodilators for enhancing therapy.Spatio-Temporal Dynamics of Hypoxia during Radiotherapy.Influence of chronic hypoxia and radiation quality on cell survival.Radiosensitising agents for the radiotherapy of cancer: advances in traditional and hypoxia targeted radiosensitisers.Bringing the heavy: carbon ion therapy in the radiobiological and clinical context.Histopathological determinants of tumor resistance: a special look to the immunohistochemical expression of carbonic anhydrase IX in human cancers.Delineation of Tumor Habitats based on Dynamic Contrast Enhanced MRIQuantitative tissue oxygen measurement in multiple organs using 19F MRI in a rat modelHypoxia as a Biomarker and for Personalized Radiation Oncology.Prognostic value of HIF-1α expression during fractionated irradiation.Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro.Effect of hyperoxygenation on tissue pO2 and its effect on radiotherapeutic efficacy of orthotopic F98 gliomasRadiosynthesis of the tumor hypoxia marker [18F]TFMISO via O-[18F]trifluoroethylation reveals a striking difference between trifluoroethyl tosylate and iodide in regiochemical reactivity toward oxygen nucleophilesPhotosensitized oxidation of hypoxanthine and xanthine by aluminum phthalocyanine tetrasulfonate. Role of the alkylating quinone 2,5-dichloro-diaziridinyl-1,4-benzoquinone.Design considerations for open-well microfluidic platforms for hypoxic cell studies.Prognostic implications of the co-detection of the urokinase plasminogen activator system and osteopontin in patients with non-small-cell lung cancer undergoing radiotherapy and correlation with gross tumor volume.P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients.
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P2860
Detection and specific targeting of hypoxic regions within solid tumors: current preclinical and clinical strategies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Detection and specific targeti ...... nical and clinical strategies.
@en
Detection and specific targeti ...... nical and clinical strategies.
@nl
type
label
Detection and specific targeti ...... nical and clinical strategies.
@en
Detection and specific targeti ...... nical and clinical strategies.
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prefLabel
Detection and specific targeti ...... nical and clinical strategies.
@en
Detection and specific targeti ...... nical and clinical strategies.
@nl
P2093
P1476
Detection and specific targeti ...... nical and clinical strategies.
@en
P2093
P304
P356
10.2174/092986708783497391
P577
2008-01-01T00:00:00Z