Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells.
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Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancerHeme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation targetA safety assessment of the antimalarial herb Artemisia annua during pregnancy in Wistar rats.Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop.Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells.Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling.Development of artemisinin compounds for cancer treatment.BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype.Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3.Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.Alterations in estrogen signalling pathways upon acquisition of anthracycline resistance in breast tumor cellsDerailed estrogen signaling and breast cancer: an authentic couple.Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells.Therapeutic applications of herbal medicines for cancer patientsAnticancer activities of artemisinin and its bioactive derivatives.Artemisinin Represses Telomerase Subunits and Induces Apoptosis in HPV-39 Infected Human Cervical Cancer Cells.Cytotoxic activity of nemorosone in human MCF-7 breast cancer cells.Transcriptome analysis of genes associated with breast cancer cell motility in response to Artemisinin treatment.
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P2860
Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Artemisinin selectively decrea ...... in human breast cancer cells.
@en
Artemisinin selectively decrea ...... in human breast cancer cells.
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type
label
Artemisinin selectively decrea ...... in human breast cancer cells.
@en
Artemisinin selectively decrea ...... in human breast cancer cells.
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Artemisinin selectively decrea ...... in human breast cancer cells.
@en
Artemisinin selectively decrea ...... in human breast cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
Artemisinin selectively decrea ...... in human breast cancer cells.
@en
P2093
Crystal N Marconett
Gary L Firestone
Jamin A Willoughby
Shyam N Sundar
Victor B Doan
P2860
P304
P356
10.1093/CARCIN/BGN214
P407
P577
2008-09-10T00:00:00Z