Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies.
about
Room-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposureMapping the protein-binding sites for iridium(iii)-based CO-releasing moleculesCarboplatin binding to histidineMass spectrometry and UV-VIS spectrophotometry of ruthenium(II) [RuClCp(mPTA)2](OSO2CF3)2 complex in solution.Reaction of the Anticancer Organometallic Ruthenium Compound, [(eta-p-Cymene)Ru(ATSC)Cl]PF(6) with Human Serum AlbuminBODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics.Pt-based drugs: the spotlight will be on proteins.Novel platinum(II) compounds with O,S bidentate ligands: synthesis, characterization, antiproliferative properties and biomolecular interactions.Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand.Identification of the structural determinants for anticancer activity of a ruthenium arene peptide conjugate.Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex.Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets.Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes.Protein metalation by metal-based drugs: X-ray crystallography and mass spectrometry studies.Controlling with light the interaction between trans-tetrapyridyl ruthenium complexes and an oligonucleotide.Ruthenium arene complexes with triphenylphosphane ligands: cytotoxicity towards pancreatic cancer cells, interaction with model proteins, and effect of ethacrynic acid substitutionProtein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozymeReactions of metallodrugs with proteins: selective binding of phosphane-based platinum(ii) dichlorides to horse heart cytochrome c probed by ESI MS coupled to enzymatic cleavage
P2860
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P2860
Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Biophysical characterisation o ...... and mass spectrometry studies.
@en
Biophysical characterisation o ...... and mass spectrometry studies.
@nl
type
label
Biophysical characterisation o ...... and mass spectrometry studies.
@en
Biophysical characterisation o ...... and mass spectrometry studies.
@nl
prefLabel
Biophysical characterisation o ...... and mass spectrometry studies.
@en
Biophysical characterisation o ...... and mass spectrometry studies.
@nl
P50
P1476
Biophysical characterisation o ...... and mass spectrometry studies.
@en
P304
P356
10.1016/J.JINORGBIO.2007.12.022
P577
2008-01-08T00:00:00Z