Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
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Systems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemAdenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cellsGIP and GLP-1, the two incretin hormones: Similarities and differencesPhosphorylation and degradation of tomosyn-2 de-represses insulin secretion.Glucose-dependent insulinotropic polypeptide prevents the progression of macrophage-driven atherosclerosis in diabetic apolipoprotein E-null mice.A naturally occurring GIP receptor variant undergoes enhanced agonist-induced desensitization, which impairs GIP control of adipose insulin sensitivityA low-glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans.β-cell function, incretin effect, and incretin hormones in obese youth along the span of glucose tolerance from normal to prediabetes to type 2 diabetes.Alogliptin: a new addition to the class of DPP-4 inhibitors.The role of incretins in glucose homeostasis and diabetes treatment.Preventive effect of dipeptidyl peptidase-4 inhibitor on atherosclerosis is mainly attributable to incretin's actions in nondiabetic and diabetic apolipoprotein E-null miceIncretin responses to oral glucose load in Japanese non-obese healthy subjects.Effects of glucose-dependent insulinotropic polypeptide on gastric emptying, glycaemia and insulinaemia during critical illness: a prospective, double blind, randomised, crossover study.Unraveling pancreatic islet biology by quantitative proteomics.Ubiquitination of G protein-coupled receptors: functional implications and drug discovery.Protective effects of GLP-1 on glomerular endothelium and its inhibition by PKCβ activation in diabetesGeniposide promotes beta-cell regeneration and survival through regulating β-catenin/TCF7L2 pathwayResistin knockout mice exhibit impaired adipocyte glucose-dependent insulinotropic polypeptide receptor (GIPR) expression.The effect of exogenous glucose-dependent insulinotropic polypeptide in combination with glucagon-like peptide-1 on glycemia in the critically ill.Exogenous glucose-dependent insulinotropic polypeptide worsens post prandial hyperglycemia in type 2 diabetesMolecular mechanisms underlying nutrient detection by incretin-secreting cells.Glucose-dependent insulinotropic polypeptide: from pathophysiology to therapeutic opportunities in obesity-associated disorders.Alogliptin benzoate for the treatment of type 2 diabetes.Molecular Pharmacology of the Incretin Receptors.The New Biology and Pharmacology of Glucagon.Uncertainties around incretin-based therapies: A literature review.Depletion of PAK1 enhances ubiquitin-mediated survivin degradation in pancreatic β-cells.Regulation of G Protein-Coupled Receptors by Ubiquitination.GLP-1 receptor expression within the human heart.Association of incretin receptors genetic polymorphisms with type 2 diabetes mellitus in Egyptian patients.
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P2860
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 May 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
@en
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
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type
label
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
@en
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
@nl
prefLabel
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
@en
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
@nl
P2093
P2860
P921
P1476
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
@en
P2093
Dariush Elahi
Denis C Muller
Mauren F A Livak
Michel Bernier
Olga D Carlson
Stuart Maudsley
P2860
P304
P356
10.1152/AJPENDO.00070.2007
P577
2007-05-15T00:00:00Z