Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
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The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer TherapyTechnological considerations for genome-guided diagnosis and management of cancerWrit large: Genomic dissection of the effect of cellular environment on immune responseThe Receptor Tyrosine Kinase AXL in Cancer ProgressionSingle-Cell Transcriptomics Bioinformatics and Computational ChallengesReconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunitiesImplementing Genome-Driven Oncology.Massively parallel digital transcriptional profiling of single cellsMeasuring intratumor heterogeneity by network entropy using RNA-seq data.Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapiesTranscriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulationAn Immune Atlas of Clear Cell Renal Cell Carcinoma.Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer.Indicators of responsiveness to immune checkpoint inhibitorsCancer heterogeneity is not compatible with one unique cancer cell metabolic mapSingle-cell entropy for accurate estimation of differentiation potency from a cell's transcriptomeReconstructing cell cycle pseudo time-series via single-cell transcriptome data.Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance.Underexpression of Specific Interferon Genes Is Associated with Poor Prognosis of MelanomaDynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitorData resources for the identification and interpretation of actionable mutations by clinicians.Identification of innate lymphoid cells in single-cell RNA-Seq data.Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell linesContribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis.Personalized Prediction of Proliferation Rates and Metabolic Liabilities in Cancer Biopsies.Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state.Studying hematopoiesis using single-cell technologies.Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.A feature selection method based on multiple kernel learning with expression profiles of different typesPRODUCTION OF A PRELIMINARY QUALITY CONTROL PIPELINE FOR SINGLE NUCLEI RNA-SEQ AND ITS APPLICATION IN THE ANALYSIS OF CELL TYPE DIVERSITY OF POST-MORTEM HUMAN BRAIN NEOCORTEX.Increased gene expression noise in human cancers is correlated with low p53 and immune activities as well as late stage cancer.Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq.Massively parallel single-nucleus RNA-seq with DroNc-seq.Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer.Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes.A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications.Comprehensive single-cell transcriptional profiling of a multicellular organism.Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.
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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
@en
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
@nl
type
label
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
@en
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
@nl
prefLabel
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
@en
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
@nl
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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
@en
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Aleksandr Y Andreev
Aleth Gaillard
Alex S Genshaft
Alexandra-Chloé Villani
Asaf Rotem
Benjamin Izar
Carly G K Ziegler
Charles H Yoon
Christine Lian
Christopher Rodman
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P304
P356
10.1126/SCIENCE.AAD0501
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P577
2016-04-01T00:00:00Z