Update on trimetrexate, a folate antagonist with antineoplastic and antiprotozoal properties.
about
Structure and dynamics in solution of the complex of lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexateExperimentally validated novel inhibitors of Helicobacter pylori phosphopantetheine adenylyltransferase discovered by virtual high-throughput screeningTargeting enzymes to cancers--new developments.Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake.A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.
P2860
Update on trimetrexate, a folate antagonist with antineoplastic and antiprotozoal properties.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 1991
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@en
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@nl
type
label
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@en
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@nl
prefLabel
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@en
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@nl
P2860
P1433
P1476
Update on trimetrexate, a fola ...... and antiprotozoal properties.
@en
P2093
P2860
P304
P356
10.3109/07357909109044227
P577
1991-01-01T00:00:00Z