Purinergic P2X7 receptors mediate ATP-induced saliva secretion by the mouse submandibular gland.
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Molecular and functional properties of P2X receptors--recent progress and persisting challengesAquaporins in Salivary Glands: From Basic Research to Clinical ApplicationsMolecular mechanism of pancreatic and salivary gland fluid and HCO3 secretionPurinergic signalling in the gastrointestinal tract and related organs in health and diseaseExtracellular ATP and P2Y2 receptors mediate intercellular Ca(2+) waves induced by mechanical stimulation in submandibular gland cells: Role of mitochondrial regulation of store operated Ca(2+) entry.Characterization of P2X7 purinergic receptors and their function in rat lacrimal gland.Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice.Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cellsThe P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice.P2X(7) receptor antagonists display agonist-like effects on cell signaling proteins.Activation of ERK1/2 by store-operated calcium entry in rat parotid acinar cells.Cholinergic agonists activate P2X7 receptors to stimulate protein secretion by the rat lacrimal gland.Rat submandibular glands secrete nanovesicles with NTPDase and 5'-nucleotidase activities.A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary glandAe4 (Slc4a9) Anion Exchanger Drives Cl- Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells.Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockoutsP2X7 receptor activation induces inflammatory responses in salivary gland epithelium.Crosstalk between purinergic receptors and canonical signaling pathways in the mouse salivary glandTRPV4 activation in mouse submandibular gland modulates Ca2+ influx and salivation.P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice.P2X7-mediated chemoprevention of epithelial cancers.Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction.Purinergic signalling in epithelial ion transport: regulation of secretion and absorption.Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors.Exciting and not so exciting roles of pannexins.Functional interactions between P2X4 and P2X7 receptors from mouse salivary epithelia.Spontaneous oscillations in intracellular Ca(2+) concentration via purinergic receptors elicit transient cell swelling in rat parotid ducts.Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells.Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms.Effect of P2X(7) receptor knockout on exocrine secretion of pancreas, salivary glands and lacrimal glands.Ectonucleotidases in the digestive system: focus on NTPDase3 localization.P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy.Proteomic analysis reveals an impaired Ca2+/AQP5 pathway in the submandibular gland in hypertension.The P2X7 receptor-inflammasome complex has a role in modulating the inflammatory response in primary Sjögren's syndrome.Distinct regulation by lipopolysaccharides of the expression of interleukin-1β by murine macrophages and salivary glands.
P2860
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P2860
Purinergic P2X7 receptors mediate ATP-induced saliva secretion by the mouse submandibular gland.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Purinergic P2X7 receptors medi ...... the mouse submandibular gland.
@en
Purinergic P2X7 receptors medi ...... the mouse submandibular gland.
@nl
type
label
Purinergic P2X7 receptors medi ...... the mouse submandibular gland.
@en
Purinergic P2X7 receptors medi ...... the mouse submandibular gland.
@nl
prefLabel
Purinergic P2X7 receptors medi ...... the mouse submandibular gland.
@en
Purinergic P2X7 receptors medi ...... the mouse submandibular gland.
@nl
P2093
P2860
P356
P1476
Purinergic P2X7 receptors medi ...... the mouse submandibular gland
@en
P2093
David A Brown
James E Melvin
Mireya Gonzalez-Begne
Tetsuji Nakamoto
Victor G Romanenko
P2860
P304
P356
10.1074/JBC.M808597200
P407
P577
2008-12-19T00:00:00Z