GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis
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GM-CSF: An immune modulatory cytokine that can suppress autoimmunityNeuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE).A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APCRegulatory T cells in multiple sclerosis and myasthenia gravis.Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiencyDendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes.IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells.GM-CSF-neuroantigen fusion proteins reverse experimental autoimmune encephalomyelitis and mediate tolerogenic activity in adjuvant-primed environments: association with inflammation-dependent, inhibitory antigen presentation.Suppressive effects on the immune response and protective immunity to a JEV DNA vaccine by co-administration of a GM-CSF-expressing plasmid in miceGM-CSF-induced, bone-marrow-derived dendritic cells can expand natural Tregs and induce adaptive Tregs by different mechanisms.How tolerogenic dendritic cells induce regulatory T cellsDendritic cell control of tolerogenic responses.Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice.Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity.GM-CSF-induced regulatory T cells selectively inhibit anti-acetylcholine receptor-specific immune responses in experimental myasthenia gravisRecombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis.Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy.Cytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosisGranulocyte macrophage colony-stimulating factor treatment of a patient in myasthenic crisis: effects on regulatory T cells.GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn's disease.Functional defect in regulatory T cells in myasthenia gravis.Mast cell mediators in tolerance.GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages.DNA and protein co-administration induces tolerogenic dendritic cells through DC-SIGN mediated negative signalsSoluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signalingGM-CSF alters dendritic cells in autoimmune diseases.Granulocyte macrophage colony-stimulating factor and the intestinal innate immune cell homeostasis in Crohn's disease.Murine and Human Model Systems for the Study of Dendritic Cell Immunobiology.The role of T regulatory cells in immunopathogenesis of myasthenia gravis: implications for therapeutics.Induction on differentiation and modulation of bone marrow progenitor of dendritic cell by methionine enkephalin (MENK).Therapeutic vaccines in metastatic castration-resistant prostate cancer: principles in clinical trial design.OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells.Depletion of CD4+ CD25+ regulatory T cells confers susceptibility to experimental autoimmune encephalomyelitis (EAE) in GM-CSF-deficient Csf2-/- mice.Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF+ T Lymphocytes.Ex vivo expansion of human Tregs by rabbit ATG is dependent on intact STAT3-signaling in CD4⁺ T cells and requires the presence of monocytes.N-3 polyunsaturated fatty acids restore Th17 and Treg balance in collagen antibody-induced arthritis.Combination immunotherapy with prostate GVAX and ipilimumab: safety and toxicity.Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson's disease.Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells.Identification of a Novel OX40L Dendritic Cell Subset That Selectively Expands Regulatory T cells
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GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
GM-CSF-induced CD11c+CD8a--den ...... sion of autoimmune thyroiditis
@en
GM-CSF-induced CD11c+CD8a--den ...... ion of autoimmune thyroiditis.
@nl
type
label
GM-CSF-induced CD11c+CD8a--den ...... sion of autoimmune thyroiditis
@en
GM-CSF-induced CD11c+CD8a--den ...... ion of autoimmune thyroiditis.
@nl
prefLabel
GM-CSF-induced CD11c+CD8a--den ...... sion of autoimmune thyroiditis
@en
GM-CSF-induced CD11c+CD8a--den ...... ion of autoimmune thyroiditis.
@nl
P2093
P2860
P356
P1476
GM-CSF-induced CD11c+CD8a--den ...... sion of autoimmune thyroiditis
@en
P2093
Balaji B Ganesh
Bellur S Prabhakar
Chenthamarakshan Vasu
Donald M Cheatem
Jian Rong Sheng
P2860
P304
P356
10.1093/INTIMM/DXN147
P577
2009-01-27T00:00:00Z