Role of mechanical stress in regulating airway surface hydration and mucus clearance rates
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A microfluidic device to apply shear stresses to polarizing ciliated airway epithelium using air flowAirway Epithelial Cell Cilia and Obstructive Lung DiseaseAirway hydration and COPDResponse of Differentiated Human Airway Epithelia to Alcohol Exposure and Klebsiella Pneumoniae ChallengeTranscriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cellsEngineering airway epitheliumAirway wall stiffening increases peak wall shear stress: a fluid-structure interaction study in rigid and compliant airways.Continuous mucociliary transport by primary human airway epithelial cells in vitro.High-resolution mucociliary transport measurement in live excised large animal trachea using synchrotron X-ray imaging.Model demonstrates functional purpose of the nasal cycle.Effect of epithelium ATP release on cyclic pressure-induced airway mucus secretion.Purinergic receptors in airway epithelia.Extracellular ATP signaling in plants.Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.An autoregulatory mechanism governing mucociliary transport is sensitive to mucus loadFunctional apical large conductance, Ca2+-activated, and voltage-dependent K+ channels are required for maintenance of airway surface liquid volume.Infection by Toxoplasma gondii, a severe parasite in neonates and AIDS patients, causes impaired anion secretion in airway epithelia.Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores.A pilot study of the impact of high-frequency chest wall oscillation in chronic obstructive pulmonary disease patients with mucus hypersecretion.Cilia dysfunction in lung disease.Suppression of adenosine-activated chloride transport by ethanol in airway epitheliaEffects of treadmill exercise versus Flutter® on respiratory flow and sputum properties in adults with cystic fibrosis: a randomised, controlled, cross-over trial.Tissue factor-bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo.A mechanochemical model for auto-regulation of lung airway surface layer volume.A multiscale MDCT image-based breathing lung model with time-varying regional ventilationCoupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling.Rhythmic pressure waves induce mucin5AC expression via an EGFR-mediated signaling pathway in human airway epithelial cells.Moderate intensity exercise mediates comparable increases in exhaled chloride as albuterol in individuals with cystic fibrosis.Multiscale image-based modeling and simulation of gas flow and particle transport in the human lungsExhaled breath condensate detects baseline reductions in chloride and increases in response to albuterol in cystic fibrosis patients.Resolution of cell-mediated airways diseases.Does passive smoking have an effect on nasal mucociliary clearance?The touching story of purinergic signaling in epithelial and endothelial cells.Airway gas flow.Structure and function of the mucus clearance system of the lung.Bioreactor for the long-term culture of lung tissue.Cilia and Mucociliary Clearance.ATP Release from Human Airway Epithelial Cells Exposed to Staphylococcus aureus Alpha-Toxin.Direct monitoring of pulmonary disease treatment biomarkers using plasmonic gold nanorods with diffusion-sensitive OCT.Evaluation of nasal mucociliary activity in patients with chronic renal failure.
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Role of mechanical stress in regulating airway surface hydration and mucus clearance rates
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 08 June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role of mechanical stress in r ...... tion and mucus clearance rates
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Role of mechanical stress in r ...... ion and mucus clearance rates.
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type
label
Role of mechanical stress in r ...... tion and mucus clearance rates
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Role of mechanical stress in r ...... ion and mucus clearance rates.
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prefLabel
Role of mechanical stress in r ...... tion and mucus clearance rates
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Role of mechanical stress in r ...... ion and mucus clearance rates.
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P2860
P1476
Role of mechanical stress in r ...... tion and mucus clearance rates
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Brian Button
Richard C Boucher
University of North Carolina Virtual Lung Group
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P304
P356
10.1016/J.RESP.2008.04.020
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2008-06-08T00:00:00Z