Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
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VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complexGPR56 Regulates VEGF production and angiogenesis during melanoma progressionVascular heterogeneity and targeting: the role of YKL-40 in glioblastoma vascularizationThe evolution of endothelial regulatory paradigms in cancer biology and vascular repairPoly-s-nitrosated albumin as a safe and effective multifunctional antitumor agent: characterization, biochemistry and possible future therapeutic applicationsMouse models for studying angiogenesis and lymphangiogenesis in cancerTumor cell autophagy as an adaptive response mediating resistance to treatments such as antiangiogenic therapyDetection of rapalog-mediated therapeutic response in renal cancer xenografts using ⁶⁴Cu-bevacizumab immunoPETPhotoacoustic microscopy of arteriovenous shunts and blood diffusion in early-stage tumors.Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinomaThe Theranostic Path to Personalized NanomedicineModeling tumor microenvironments in vitro.Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors.Toll-like receptor agonists in cancer therapy.Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium studyEvolutionary dynamics of carcinogenesis and why targeted therapy does not work.The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma ModelBiomarkers of response and resistance to antiangiogenic therapy.Stromal endothelial cells directly influence cancer progression.CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates.The shunt problem: control of functional shunting in normal and tumour vasculature.Intratumoral drug delivery with nanoparticulate carriers.Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosisTumor-surrogate blood vessel subtypes exhibit differential susceptibility to anti-VEGF therapyTumor microenvironment and progression.Larger therapeutic window for steroid versus VEGF-A inhibitor in inflammatory angiogenesis: surprisingly similar impact on leukocyte infiltration.The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signalingLack of efficacy of bevacizumab + irinotecan in cases of pediatric recurrent ependymoma--a Pediatric Brain Tumor Consortium study.Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targetsImplications of neurovascular uncoupling in functional magnetic resonance imaging (fMRI) of brain tumors.Nanomedicines for Endothelial Disorders.The vasculature: a vessel for bone metastasis.Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis.Breast cancer cell-derived matrix supports vascular morphogenesis.Vasohibin-1 expression in endothelium of tumor blood vessels regulates angiogenesis.Biologically conformal treatment: biomarkers and functional imaging in radiation oncology.The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis.Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase.Simultaneous imaging of tumor oxygenation and microvascular permeability using Overhauser enhanced MRI.
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Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@en
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@nl
type
label
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@en
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@nl
prefLabel
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@en
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@nl
P356
P1476
Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.
@en
P2093
Rakesh K Jain
P2888
P304
P356
10.1038/NRC2346
P407
P577
2008-04-01T00:00:00Z