Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect.
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Annexin 1 induced by anti-inflammatory drugs binds to NF-kappaB and inhibits its activation: anticancer effects in vitro and in vivoTargeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in micePhospho-aspirin-2 (MDC-22) inhibits estrogen receptor positive breast cancer growth both in vitro and in vivo by a redox-dependent effectNSAIDs, Mitochondria and Calcium Signaling: Special Focus on Aspirin/SalicylatesPhospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice.Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: a redox/polyamine-dependent effectThe novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats.Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stressOxidative stress mediates through apoptosis the anticancer effect of phospho-nonsteroidal anti-inflammatory drugs: implications for the role of oxidative stress in the action of anticancer agentsChemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds.Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stressPhospho-Aspirin (MDC-22) Prevents Pancreatic Carcinogenesis in Mice.Prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs), more than meets the eye: a critical review.The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells.Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety.The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse.Structure-activity relationship study of novel anticancer aspirin-based compounds.The differential cell signaling effects of two positional isomers of the anticancer NO-donating aspirin.Prodrugs Bioactivated to Quinones Target NF-κB and Multiple Protein Networks: Identification of the Quinonome.
P2860
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P2860
Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
@en
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
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type
label
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
@en
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
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prefLabel
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
@en
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
@nl
P2093
P2860
P356
P1433
P1476
Phosphoaspirin (MDC-43), a nov ...... rin: a redox-dependent effect.
@en
P2093
Basil Rigas
Gerardo G Mackenzie
Onika T Murray
Wenping Zhao
Zhiquan Zhang
P2860
P304
P356
10.1093/CARCIN/BGP015
P407
P577
2009-01-09T00:00:00Z