Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication.
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Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and diseaseAtomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor KinasesThe expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity.Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitorsMolecular basis for small molecule inhibition of G protein-coupled receptor kinasesIdentification and characterization of amlexanox as a G protein-coupled receptor kinase 5 inhibitorMicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death.Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed InhibitorThe evolving impact of g protein-coupled receptor kinases in cardiac health and diseaseMyocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases."Canonical and non-canonical actions of GRK5 in the heart"Differential Role of G Protein-Coupled Receptor Kinase 5 in Physiological Versus Pathological Cardiac HypertrophyA class of their own: exploring the nondeacetylase roles of class IIa HDACs in cardiovascular diseaseCardiomyocyte-secreted acetylcholine is required for maintenance of homeostasis in the heartRegulation of nuclear factor κB (NF-κB) in the nucleus of cardiomyocytes by G protein-coupled receptor kinase 5 (GRK5).Structural insights into G protein-coupled receptor kinase function.Apelin receptor: its responsiveness to stretch mechanisms and its potential for cardiovascular therapy.Noncanonical Roles of G Protein-coupled Receptor Kinases in Cardiovascular Signaling.Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targetingG protein-coupled receptor kinase 5: exploring its hype in cardiac hypertrophy.Grk5l controls heart development by limiting mTOR signaling during symmetry breaking.G Protein-Coupled Receptor Kinases in the Inflammatory Response and Signaling.PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) Regulates G-protein coupled Receptor Kinase 5 (GRK5) induced Cardiac Hypertrophy in vitro.Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans.
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Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 August 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Determining the absolute requi ...... ertrophy: short communication.
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Determining the absolute requi ...... ertrophy: short communication.
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Determining the absolute requi ...... ertrophy: short communication.
@en
Determining the absolute requi ...... ertrophy: short communication.
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Determining the absolute requi ...... ertrophy: short communication.
@en
Determining the absolute requi ...... ertrophy: short communication.
@nl
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Determining the absolute requi ...... ertrophy: short communication.
@en
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Jessica I Gold
Richard T Premont
Walter J Koch
Xiying Shang
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P304
P356
10.1161/CIRCRESAHA.112.273367
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P577
2012-08-02T00:00:00Z