Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
about
Bacteriophage T7 DNA polymerase - sequenaseDNA replication at the single-molecule levelChoreography of bacteriophage T7 DNA replicationDynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primaseNew insights into replisome fluidity during chromosome replicationSingle-molecule analysis of DNA replication in Xenopus egg extractsReplisome speed determines the efficiency of the Tus-Ter replication termination barrierHigh-throughput single-molecule studies of protein-DNA interactions.Many ways to loop DNA.Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery.Camera-based three-dimensional real-time particle tracking at kHz rates and Ångström accuracyReal-time single-molecule observation of rolling-circle DNA replication.Visualizing Single-molecule DNA Replication with Fluorescence MicroscopyHuman POT1 is required for efficient telomere C-rich strand replication in the absence of WRN.Replisome mechanics: lagging strand events that influence speed and processivityTwo modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complexTiming, coordination, and rhythm: acrobatics at the DNA replication fork.Direct role for the RNA polymerase domain of T7 primase in primer delivery.Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay.Genetic requirements for sensitivity of bacteriophage t7 to dideoxythymidine.Versatile single-molecule multi-color excitation and detection fluorescence setup for studying biomolecular dynamics.Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery.Probing transient protein-mediated DNA linkages using nanoconfinement.A specific docking site for DNA polymerase {alpha}-primase on the SV40 helicase is required for viral primosome activity, but helicase activity is dispensableSister acts: coordinating DNA replication and cohesion establishment.Single-molecule studies of DNA replisome function.Revisiting the central dogma one molecule at a time.E. coli DNA replication in the absence of free β clamps.DNA replication catalyzed by herpes simplex virus type 1 proteins reveals trombone loops at the fork.A new direct single-molecule observation method for DNA synthesis reaction using fluorescent replication protein A.Supported lipid bilayers and DNA curtains for high-throughput single-molecule studiesGene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication.The impact of DNA intercalators on DNA and DNA-processing enzymes elucidated through force-dependent binding kinetics.Molecular interactions in the priming complex of bacteriophage T7.Heterohexamer of 56- and 63-kDa Gene 4 Helicase-Primase of Bacteriophage T7 in DNA Replication.Exchange between Escherichia coli polymerases II and III on a processivity clamp.Primer release is the rate-limiting event in lagging-strand synthesis mediated by the T7 replisome.Single-molecule studies reveal the function of a third polymerase in the replisome.Insights into Okazaki fragment synthesis by the T4 replisome: the fate of lagging-strand holoenzyme components and their influence on Okazaki fragment sizeAn in trans interaction at the interface of the helicase and primase domains of the hexameric gene 4 protein of bacteriophage T7 modulates their activities.
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P2860
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
@en
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis.
@nl
type
label
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
@en
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis.
@nl
prefLabel
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
@en
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis.
@nl
P2093
P2860
P356
P1433
P1476
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
@en
P2093
Charles C Richardson
Joseph J Loparo
Masateru Takahashi
P2860
P2888
P304
P356
10.1038/NATURE07512
P407
P577
2008-11-23T00:00:00Z
P5875
P6179
1010212348