Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo
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Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changesAge-dependent dysregulation of innate immunityCo-administration of IL-1+IL-6+TNF-α with Mycobacterium tuberculosis infected macrophages vaccine induces better protective T cell memory than BCGKey role of T cell defects in age-related vulnerability to West Nile virusMAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infectionHallmarks of CD4 T cell immunity against influenzaMitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice.Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathwayAging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.A novel adjuvant for vaccine development in the agedImmunization of aged mice with a pneumococcal conjugate vaccine combined with an unmethylated CpG-containing oligodeoxynucleotide restores defective immunoglobulin G antipolysaccharide responses and specific CD4+-T-cell priming to young adult levelsDevelopment of effective vaccines for old mice in a tumor model.Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cellsA retrospective analysis of the Alzheimer's disease vaccine progress - The critical need for new development strategies.Influenza vaccine responses in older adults.Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.GLA-SE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults.Aging murine B cells have decreased class switch induced by anti-CD40 or BAFFThe combined molecular adjuvant CASAC enhances the CD8+ T cell response to a tumor-associated self-antigen in aged, immunosenescent mice.Immunosenescence and Challenges of Vaccination against Influenza in the Aging Population.Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment.Mononuclear phagocyte-derived interleukin-10 suppresses the innate pulmonary granuloma cytokine response in aged miceTargeting Mycobacterium tuberculosis Tumor Necrosis Factor Alpha-Downregulating Genes for the Development of Antituberculous Vaccines.T cell aging: naive but not young.Live Attenuated Leishmania donovani Centrin Knock Out Parasites Generate Non-inferior Protective Immune Response in Aged Mice against Visceral Leishmaniasis.Intrinsic versus environmental influences on T-cell responses in aging.The effect of age on the cognate function of CD4+ T cells.Homeostasis and the age-associated defect of CD4 T cells.The effect of aging on cognate function and development of immune memory.Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defectsNon-human primate models of T-cell reconstitution.Serum from exercising humans suppresses t-cell cytokine production.Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responsesNewly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigenCD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza.Mucosal adjuvant activity of flagellin in aged mice.Danger signals and nonself entity of tumor antigen are both required for eliciting effective immune responses against HER-2/neu positive mammary carcinoma: implications for vaccine designImmunity, ageing and cancer.Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responsesImmunological outcomes of exercise in older adults
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Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo
@en
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo.
@nl
type
label
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo
@en
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo.
@nl
prefLabel
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo
@en
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo.
@nl
P2093
P2860
P1476
Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo
@en
P2093
Eve M Burns
Laura Haynes
Mercedes Rincon
Sheri M Eaton
P2860
P304
P356
10.4049/JIMMUNOL.172.9.5194
P407
P577
2004-05-01T00:00:00Z