Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).

Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).

Item
http://www.wikidata.org/entity/Q37121568
Predictive biomarkers in precision medicine and drug development against lung cancerAntitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibitionProdrug oncrasin-266 improves the stability, pharmacokinetics, and safety of NSC-743380Antagonistic effect of flavonoids on NSC-741909-mediated antitumor activity via scavenging of reactive oxygen species.Development of synthetic lethality anticancer therapeutics.Analogues and derivatives of oncrasin-1, a novel inhibitor of the C-terminal domain of RNA polymerase II and their antitumor activities.Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cellsRAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.Hedgehog pathway and GLI1 isoforms in human cancer.Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present).Genetic Interactions of STAT3 and Anticancer Drug Development.Synthesis and biological evaluation of novel 6-hydrazinyl-2,4-bismorpholino pyrimidine and 1,3,5-triazine derivatives as potential antitumor agents.Anti-leukemia activity of NSC-743380 in SULT1A1-expressing acute myeloid leukemia cells is associated with inhibitions of cFLIP expression and PI3K/AKT/mTOR activities.
P2860

Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).

Item
http://www.wikidata.org/entity/Q37121568
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@en
Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@nl
type
label
Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@en
Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@nl
prefLabel
Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@en
Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@nl
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P1476
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Interruption of RNA processing ...... 3-carboxaldehyde (oncrasin-1).
@en
P2093
P2860
P304
P31
P356
10.1158/1535-7163.MCT-08-0839
P433
P478
P577
P5875
P698
P932