Cytoplasmic dynein could be key to understanding neurodegeneration.
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Exome sequencing identifies a DYNC1H1 mutation in a large pedigree with dominant axonal Charcot-Marie-Tooth diseaseCellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling.Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1(G93A) motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant miceInhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinaseMouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcriptsBehavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosisThe Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration.Aplysqualenol A binds to the light chain of dynein type 1 (DYNLL1).A novel phenotype for the dynein heavy chain mutation Loa: altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons.Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases.Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation.Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold.Dync1h1 Mutation Causes Proprioceptive Sensory Neuron Loss and Impaired Retrograde Axonal Transport of Dorsal Root Ganglion Neurons.
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Cytoplasmic dynein could be key to understanding neurodegeneration.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 March 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cytoplasmic dynein could be key to understanding neurodegeneration.
@en
Cytoplasmic dynein could be key to understanding neurodegeneration.
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type
label
Cytoplasmic dynein could be key to understanding neurodegeneration.
@en
Cytoplasmic dynein could be key to understanding neurodegeneration.
@nl
prefLabel
Cytoplasmic dynein could be key to understanding neurodegeneration.
@en
Cytoplasmic dynein could be key to understanding neurodegeneration.
@nl
P2860
P921
P356
P1433
P1476
Cytoplasmic dynein could be key to understanding neurodegeneration.
@en
P2093
Gareth T Banks
P2860
P2888
P356
10.1186/GB-2008-9-3-214
P577
2008-03-28T00:00:00Z