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Molecular determinants of magnesium homeostasis: insights from human disease

Molecular determinants of magnesium homeostasis: insights from human disease

http://www.wikidata.org/entity/Q37123833

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Mg2+-dependent gating of bacterial MgtE channel underlies Mg2+ homeostasis Magnesium modulates ROMK channel-mediated potassium secretion Mg2+-dependent interactions of ATP with the cystathionine-β-synthase (CBS) domains of a magnesium transporter Solute Carrier Family SLC41, what do we really know about it?Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.Renal, ocular, and neuromuscular involvements in patients with CLDN19 mutations.A novel nondevelopmental role of the sax-7/L1CAM cell adhesion molecule in synaptic regulation in Caenorhabditis elegans.Cellular magnesium homeostasis.The effect of acute vs chronic magnesium supplementation on exercise and recovery on resistance exercise, blood pressure and total peripheral resistance on normotensive adults.North Central Cancer Treatment Group N10C2 (Alliance): a double-blind placebo-controlled study of magnesium supplements to reduce menopausal hot flashes.'Lemonade Legs': Why do Some Patients Get Profound Hypomagnesaemia on Proton-Pump Inhibitors?Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens.Claudin-16 and claudin-19 function in the thick ascending limb.Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels.The unique nature of mg2+ channels.Magnesium-permeable TRPM6 polymorphisms in patients with meningomyelocele.The underestimated problem of using serum magnesium measurements to exclude magnesium deficiency in adults; a health warning is needed for "normal" results.Magnesium disorders: clinical experience and review of the literature.Disorders of calcium and magnesium balance: a physiology-based approach.Magnesium homeostasis and hypomagnesemia in children with malignancy.Hypomagnesemia, chronic kidney disease and cardiovascular mortality: pronounced association but unproven causation.Pathophysiology of Calcium, Phosphorus, and Magnesium Dysregulation in Chronic Kidney Disease.The safety of calcineurin inhibitors for kidney-transplant patients.A Novel Hypokalemic-Alkalotic Salt-Losing Tubulopathy in Patients with CLDN10 Mutations.ATP-dependent modulation of MgtE in Mg2+ homeostasis.Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE.Omeprazole enhances the colonic expression of the Mg(2+) transporter TRPM6.Potential antiosteoporosis effect of biodegradable magnesium implanted in STZ-induced diabetic rats.Serum magnesium in the first week of life in extremely low birth weight infants.Serum and saliva magnesium in postmenopausal women with xerostomia.Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR.Magnesium metabolism.Downregulation of transient receptor potential M6 channels as a cause of hypermagnesiuric hypomagnesemia in obese type 2 diabetic rats.Atomic mineral characteristics of Indonesian osteoporosis by high-resolution inductively coupled plasma mass spectrometry.Magnesium: Nutrition and Homoeostasis.

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Molecular determinants of magnesium homeostasis: insights from human disease

http://www.wikidata.org/entity/Q37123833

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 18 June 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Molecular determinants of magnesium homeostasis: insights from human disease

@en

Molecular determinants of magnesium homeostasis: insights from human disease.

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type

label

Molecular determinants of magnesium homeostasis: insights from human disease

@en

Molecular determinants of magnesium homeostasis: insights from human disease.

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prefLabel

Molecular determinants of magnesium homeostasis: insights from human disease

@en

Molecular determinants of magnesium homeostasis: insights from human disease.

@nl

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Journal of the American Society of Nephrology

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Molecular determinants of magnesium homeostasis: insights from human disease

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Joost G Hoenderop

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R Todd Alexander

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René J Bindels

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P2860

Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption

Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia

Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement

Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7

Magnesium deficiency: effect on bone mineral density in the mouse appendicular skeleton

Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis maps to chromosome 3q27 and is associated with mutations in the PCLN-1 gene

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

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1451-1458

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scholarly article

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10.1681/ASN.2008010098

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8

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19

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2008-06-18T00:00:00Z

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18562569

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Béésh Łikoní

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4959876

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