Multicenter, randomized, controlled trials evaluating mortality in intensive care: doomed to fail?
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Clinical review: Thinking outside the box--an iconoclastic view of current practiceDelta inflation: a bias in the design of randomized controlled trials in critical care medicine.Platelet desialylation is a novel mechanism and a therapeutic target in thrombocytopenia during sepsis: an open-label, multicenter, randomized controlled trial.Thirty years of critical care medicine.Outcomes and statistical power in adult critical care randomized trialsExamination of Setarud (IMOD™) in the management of patients with severe sepsisWhen do confounding by indication and inadequate risk adjustment bias critical care studies? A simulation study.Translational research in sepsis - an ultimate challenge?Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?Systems modeling and simulation applications for critical care medicine.Trials in adult critical care that show increased mortality of the new intervention: Inevitable or preventable mishaps?The top cited clinical research articles on sepsis: a bibliometric analysisAdvancing critical care: time to kiss the right frog.External validation of the APPS, a new and simple outcome prediction score in patients with the acute respiratory distress syndrome.Patient-important outcomes in randomized controlled trials in critically ill patients: a systematic review.Immune-modulating interventions in critically ill septic patients: pharmacological options.Registration and design alterations of clinical trials in critical care: a cross-sectional observational study.The International Multi-disciplinary Consensus Conference on Multimodality Monitoring: future directions and emerging technologies.Alternative clinical trial design in neurocritical care.Burn Shock and Resuscitation: Proceedings of a Symposium Conducted at the Meeting of the American Burn Association, Chicago, IL, 21 April 2015.Continuous glucose monitoring in the ICU: clinical considerations and consensus.Effect sizes in ongoing randomized controlled critical care trials.Predicting intervention onset in the ICU with switching state space models.Septic shock: the changing Zeitgeist of management.Hemodynamic monitoring in the era of evidence-based medicine'Chronomics' in ICU: circadian aspects of immune response and therapeutic perspectives in the critically ill."Big data" in the intensive care unit. Closing the data loop.Use of biomarkers in sepsis: many questions, few answers.Extracorporeal membrane oxygenation in adult patients with severe acute respiratory failure.External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome.Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France: A Randomized Clinical Trial.Evidence-based critical care medicine: seeing through a glass darkly.Reproducibility of clinical research in critical care: a scoping review.Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them.Research priorities in neurocritical care.Understanding vasopressor intervention and weaning: risk prediction in a public heterogeneous clinical time series database.Sample size implications of mortality definitions in sepsis: a retrospective cohort study.Inclusion and definition of acute renal dysfunction in critically ill patients in randomized controlled trials: a systematic review.There is more to septic shock than arterial hypotension and elevated lactate levels: another appeal to rethink current resuscitation strategies!
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Multicenter, randomized, controlled trials evaluating mortality in intensive care: doomed to fail?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
@en
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
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type
label
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
@en
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
@nl
prefLabel
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
@en
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
@nl
P1476
Multicenter, randomized, contr ...... ntensive care: doomed to fail?
@en
P2093
Gustavo A Ospina-Tascón
Gustavo Luiz Büchele
P304
P356
10.1097/CCM.0B013E318168EA3E
P407
P577
2008-04-01T00:00:00Z