Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression.
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Spatial epigenetic control of mono- and bistable gene expressionNegative feedback loops involving small regulatory RNAs precisely control the Vibrio harveyi quorum-sensing responseRobustness: mechanisms and consequencesPhenotypic Variability in Synthetic Biology Applications: Dealing with Noise in Microbial Gene ExpressionNetwork calisthenics: control of E2F dynamics in cell cycle entryMapping the environmental fitness landscape of a synthetic gene circuitCombinatorial gene regulation using auto-regulationEffect of promoter architecture on the cell-to-cell variability in gene expressionAdjusting phenotypes by noise controlCombined model of intrinsic and extrinsic variability for computational network design with application to synthetic biologyCholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2Quantifying intrinsic and extrinsic variability in stochastic gene expression modelsAutoregulation and heterogeneity in expression of human Cripto-1Implementation Considerations, Not Topological Differences, Are the Main Determinants of Noise Suppression Properties in Feedback and Incoherent Feedforward CircuitsRate of environmental change determines stress response specificity.Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.A structured population modeling framework for quantifying and predicting gene expression noise in flow cytometry data.Adaptable functionality of transcriptional feedback in bacterial two-component systems.Network inference and network response identification: moving genome-scale data to the next level of biological discoveryProgramming mRNA decay to modulate synthetic circuit resource allocationCell cycle-dependent variations in protein concentration.Tuning and controlling gene expression noise in synthetic gene networks.Digital and analog gene circuits for biotechnology.Negative feedback in genetic circuits confers evolutionary resilience and capacitance.Negative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coliLsrR quorum sensing "switch" is revealed by a bottom-up approachMicroRNA-mediated positive feedback loop and optimized bistable switch in a cancer network Involving miR-17-92.Base pairing small RNAs and their roles in global regulatory networks.Network reconstruction reveals new links between aging and calorie restriction in yeast.Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range.Modeling suggests that gene circuit architecture controls phenotypic variability in a bacterial persistence network.Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops.Synthetic mammalian transgene negative autoregulation.Promoter strength driving TetR determines the regulatory properties of Tet-controlled expression systemsFine-tuning gene networks using simple sequence repeats.Bimodal gene expression in noncooperative regulatory systemsNoise propagation in gene regulation networks involving interlinked positive and negative feedback loops.Building robust transcriptomes with master splicing factorsAphA and LuxR/HapR reciprocally control quorum sensing in vibriosNoise decomposition of intracellular biochemical signaling networks using nonequivalent reporters
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P2860
Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Negative autoregulation linear ...... erogeneity of gene expression.
@en
Negative autoregulation linear ...... erogeneity of gene expression.
@nl
type
label
Negative autoregulation linear ...... erogeneity of gene expression.
@en
Negative autoregulation linear ...... erogeneity of gene expression.
@nl
prefLabel
Negative autoregulation linear ...... erogeneity of gene expression.
@en
Negative autoregulation linear ...... erogeneity of gene expression.
@nl
P2093
P2860
P356
P1476
Negative autoregulation linear ...... erogeneity of gene expression.
@en
P2093
Dmitry Nevozhay
Gábor Balázsi
Kevin F Murphy
Kresimir Josic
Rhys M Adams
P2860
P304
P356
10.1073/PNAS.0809901106
P407
P577
2009-03-11T00:00:00Z