The IR4 auxiliary regulatory protein expands the in vitro host range of equine herpesvirus 1 and is essential for pathogenesis in the murine model.
about
The equine herpesvirus-1 (EHV-1) IR3 transcript downregulates expression of the IE gene and the absence of IR3 gene expression alters EHV-1 biological properties and virulence.Properties of an equine herpesvirus 1 mutant devoid of the internal inverted repeat sequence of the genomic short region.The UL4 protein of equine herpesvirus 1 is not essential for replication or pathogenesis and inhibits gene expression controlled by viral and heterologous promoters.The early UL3 gene of equine herpesvirus-1 encodes a tegument protein not essential for replication or virulence in the mouseHSV-1 ICP22: hijacking host nuclear functions to enhance viral infection.
P2860
The IR4 auxiliary regulatory protein expands the in vitro host range of equine herpesvirus 1 and is essential for pathogenesis in the murine model.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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2008年學術文章
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2008年學術文章
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name
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@en
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@nl
type
label
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@en
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@nl
prefLabel
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@en
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@nl
P2093
P2860
P1433
P1476
The IR4 auxiliary regulatory p ...... hogenesis in the murine model.
@en
P2093
Dennis J O'Callaghan
Jonathan E Breitenbach
Paul D Ebner
P2860
P304
P356
10.1016/J.VIROL.2008.10.017
P407
P577
2008-11-13T00:00:00Z