Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production. - Wikidata - wikimedia - TriplyDB

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

http://www.wikidata.org/entity/Q37127299

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Metabolic functions of FABPs--mechanisms and therapeutic implications Energy metabolism in the liver Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes Adipocytokines in obesity and metabolic disease.A role for novel adipose tissue-secreted factors in obesity-related carcinogenesis.Fatty acid binding protein 4 deficiency protects against oxygen-induced retinopathy in mice Serum FABP5 concentration is a potential biomarker for residual risk of atherosclerosis in relation to cholesterol efflux from macrophages Fatty acid-binding protein FABP4 mechanistically links obesity with aggressive AML by enhancing aberrant DNA methylation in AML cells.Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity.Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance Elevation of circulating fatty acid-binding protein 4 is independently associated with left ventricular diastolic dysfunction in a general population.Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity.Urinary excretion of fatty acid-binding protein 4 is associated with albuminuria and renal dysfunction.Control of metabolic adaptation to fasting by dILP6-induced insulin signaling in Drosophila oenocytes Fatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases.Evolutionary game theory: cells as players.Immune regulation of metabolic homeostasis in health and disease.Possible Increase in Serum FABP4 Level Despite Adiposity Reduction by Canagliflozin, an SGLT2 Inhibitor.Cardiomyocyte Overexpression of FABP4 Aggravates Pressure Overload-Induced Heart Hypertrophy.Transcriptome and Metabolome Analyses in Exogenous FABP4- and FABP5-Treated Adipose-Derived Stem Cells Reduction of serum FABP4 level by sitagliptin, a DPP-4 inhibitor, in patients with type 2 diabetes mellitus.Reduction of circulating FABP4 level by treatment with omega-3 fatty acid ethyl esters.Gsα deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight.Loss of Fatty Acid Binding Protein 4/aP2 Reduces Macrophage Inflammation Through Activation of SIRT3 Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress.Cytokine-like Activity of Liver Type Fatty Acid Binding Protein (L-FABP) Inducing Inflammatory Cytokine Interleukin-6.What we talk about when we talk about fat.A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes.The control of insulin secretion by adipokines: current evidence for adipocyte-beta cell endocrine signalling in metabolic homeostasis.Interorgan Communication Pathways in Physiology: Focus on Drosophila.Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment.Hepatic Induction of Fatty Acid Binding Protein 4 Plays a Pathogenic Role in Sepsis in Mice.NAFLD and diabetes mellitus.Adipose tissue: between the extremes.Plasma Levels of Fatty Acid-Binding Protein 4, Retinol-Binding Protein 4, High-Molecular-Weight Adiponectin, and Cardiovascular Mortality Among Men With Type 2 Diabetes: A 22-Year Prospective Study.Lipolytic efficacy of alginate double-layer nanoemulsion containing oleoresin capsicum in differentiated 3T3-L1 adipocytes.Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes.Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling.Suppression of adipocyte differentiation and lipid accumulation by stearidonic acid (SDA) in 3T3-L1 cells Ectopic Fatty Acid-Binding Protein 4 Expression in the Vascular Endothelium is Involved in Neointima Formation After Vascular Injury.

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Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

http://www.wikidata.org/entity/Q37127299

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on May 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

@en

Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

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type

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Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

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Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

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prefLabel

Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

@en

Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

@nl

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J.CMET.2013.04.012

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Cell Metabolism

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Adipocyte lipid chaperone AP2 ...... ng hepatic glucose production.

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Ariel White

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Baris C Ercal

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Gökhan S Hotamisligil

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Gürol Tuncman

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Haiming Cao

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Jared R Mayers

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Karen Inouye

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Lisa M Rickey

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M Furkan Burak

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Masato Furuhashi

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P2860

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

Inflammation and metabolic disorders

Obesity is associated with macrophage accumulation in adipose tissue

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease

Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele

Adipocytes as regulators of energy balance and glucose homeostasis

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768-778

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scholarly article

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10.1016/J.CMET.2013.04.012

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5

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17

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2013-05-01T00:00:00Z

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236689643

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23663740

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molecular chaperones

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3755450

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