Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells
about
Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemiaAntidepressants, but not antipsychotics, modulate GR function in human whole blood: an insight into molecular mechanisms.Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells.Inherited genetic variation in childhood acute lymphoblastic leukemia.Chronic lymphocytic leukemia and B and T cells differ in their response to cyclic nucleotide phosphodiesterase inhibitors.Targeting cAMP in chronic lymphocytic leukemia: a pathway-dependent approach for the treatment of leukemia and lymphoma.Safety and Pharmacodynamics of the PDE4 Inhibitor Roflumilast in Advanced B-cell Malignancies.Phosphodiesterase-4 inhibition improves corticosteroid insensitivity in pulmonary endothelial cells under oxidative stress.Glial restricted precursor cell transplant with cyclic adenosine monophosphate improved some autonomic functions but resulted in a reduced graft size after spinal cord contusion injury in rats.Converting cell lines representing hematological malignancies from glucocorticoid-resistant to glucocorticoid-sensitive: signaling pathway interactions.Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells.Synergistic targeting of the regulatory and catalytic subunits of PI3Kδ in mature B cell malignancies.Roflumilast restores cAMP/PKA/CREB signaling axis for FtMt-mediated tumor inhibition of ovarian cancer.
P2860
Q28943431-F3478255-1C7C-470B-A08D-2F11DA2B0EEDQ34315494-84C9ADA9-B033-4AC5-AAC8-B603DA929F56Q35096709-5C3A9B3E-83F4-4CF3-AAE4-593935968C42Q35784497-5AA50104-643B-44B9-BEBE-C86D3F6F0E7EQ37178775-AAB252CE-EED7-42CF-81E6-93F628F38476Q38104404-8D737053-3D3A-47F0-BE46-84710BBDFBFAQ39472422-6977E373-6642-4E4B-9350-4DF4B8BF6B15Q39526549-ED1F84DB-A33C-484A-A26D-D2509541B734Q39821814-48640746-F777-4943-A312-A3C520862859Q39916105-DB5CAFE7-1A5A-4294-AED1-8404B082FCBFQ43225747-64061E7C-1DE0-45B6-BF32-B4B2442114B5Q47300115-8C2A1FC7-D09C-41BE-845F-A010AADA7652Q49468702-A6A1FA3B-EF15-4F18-9D51-D59446856952
P2860
Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Phosphodiesterase 4 inhibitors ...... irculating hematopoietic cells
@en
Phosphodiesterase 4 inhibitors ...... rculating hematopoietic cells.
@nl
type
label
Phosphodiesterase 4 inhibitors ...... irculating hematopoietic cells
@en
Phosphodiesterase 4 inhibitors ...... rculating hematopoietic cells.
@nl
prefLabel
Phosphodiesterase 4 inhibitors ...... irculating hematopoietic cells
@en
Phosphodiesterase 4 inhibitors ...... rculating hematopoietic cells.
@nl
P2093
P2860
P1476
Phosphodiesterase 4 inhibitors ...... irculating hematopoietic cells
@en
P2093
Adam Lerner
Anthony Makkinje
John A Meyers
Jorge Chaves
Josephine Taverna
P2860
P304
P356
10.1158/1078-0432.CCR-07-0276
P407
P577
2007-08-01T00:00:00Z