Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
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Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acidMitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug developmentCurrent and future pharmacological treatment strategies in X-linked adrenoleukodystrophyDrug Induced Steatohepatitis: An Uncommon Culprit of a Common DiseaseXenobiotic perturbation of ER stress and the unfolded protein responseInflammasomes in pancreatic physiology and diseaseM-current preservation contributes to anticonvulsant effects of valproic acid.Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slicesSeizure control by ketogenic diet-associated medium chain fatty acidsImpact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data.Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma CellsEvaluation of the Potential Risk of Drugs to Induce Hepatotoxicity in Human-Relationships between Hepatic Steatosis Observed in Non-Clinical Toxicity Study and Hepatotoxicity in HumansMolecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome.Treatment of mitochondrial disorders.Chromatin remodeling, cell proliferation and cell death in valproic acid-treated HeLa cellsWhole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.Mitochondria, energetics, epigenetics, and cellular responses to stress.Valproic acid-associated acute liver failure in children: case report and analysis of liver transplantation outcomes in the United States.A modern approach to the treatment of mitochondrial diseaseTreatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genesRole of isovaleryl-CoA dehydrogenase and short branched-chain acyl-CoA dehydrogenase in the metabolism of valproic acid: implications for the branched-chain amino acid oxidation pathway.Brief report novel mechanism for valproate-induced teratogenicity.Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes.Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.Psychiatric symptoms of patients with primary mitochondrial DNA disordersHypothermia and valproic acid activate prosurvival pathways after hemorrhage.Mitochondria as a target of environmental toxicants.Glucose metabolism as a target of histone deacetylase inhibitors.Valproic Acid and Hepatic Steatosis: A Possible Link? About a Case Report.Valproic acid is a novel activator of AMP-activated protein kinase and decreases liver mass, hepatic fat accumulation, and serum glucose in obese mice.Carnitine in the treatment of valproic acid-induced toxicity.Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage.Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs.The Role of Renal Replacement Therapy in the Management of Pharmacologic Poisonings.A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial networks.The mechanistic basis for the induction of hepatic steatosis by xenobiotics.Evidence for a potential protective effect of carnitine-pantothenic acid co-treatment on valproic acid-induced hepatotoxicity.SEURAT-1 liver gold reference compounds: a mechanism-based review.Mechanistic review of drug-induced steatohepatitisMitochondrial fusion, fission, and mitochondrial toxicity.
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Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 04 April 2008
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@en
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@nl
type
label
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@en
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@nl
prefLabel
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@en
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@nl
P2093
P2860
P1476
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
@en
P2093
C C P Aires
I Tavares de Almeida
J P N Ruiter
M F B Silva
P B M Luis
R J A Wanders
P2860
P2888
P304
P356
10.1007/S10545-008-0841-X
P577
2008-04-04T00:00:00Z