Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?
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Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesisThe Ca(2+) -activated Cl(-) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesisRole of serine-threonine phosphoprotein phosphatases in smooth muscle contractilityCalcium-dependent phospholipid scramblase activity of TMEM16 protein family membersInhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell LinesCalmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channelsMechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blockerThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsAcidic amino acids in the first intracellular loop contribute to voltage- and calcium- dependent gating of anoctamin1/TMEM16A.The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesisAnoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca2+.ANO10 mutations cause ataxia and coenzyme Q₁₀ deficiencyCommon variants associated with general and MMR vaccine-related febrile seizures.Mapping of long-range INS promoter interactions reveals a role for calcium-activated chloride channel ANO1 in insulin secretion.Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channelsCharacterization of Cardiac Anoctamin1 Ca²⁺-Activated Chloride Channels and Functional Role in Ischemia-Induced ArrhythmiasAnoctamin 6 regulates C2C12 myoblast proliferationContribution of calcium-activated chloride channel to elevated pulmonary artery pressure in pulmonary arterial hypertension induced by high pulmonary blood flow.Multiple transcripts of anoctamin genes expressed in the mouse submandibular salivary gland.Ano1/TMEM16A Overexpression Is Associated with Good Prognosis in PR-Positive or HER2-Negative Breast Cancer Patients following Tamoxifen Treatment.Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice.Identification of a lipid scrambling domain in ANO6/TMEM16F.Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina.Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.Molecular and functional expression of cation-chloride cotransporters in dorsal root ganglion neurons during postnatal maturationGenetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy.Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.A Role of TMEM16E Carrying a Scrambling Domain in Sperm Motility.Salt, chloride, bleach, and innate host defense.Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2Whole exome sequencing links dental tumor to an autosomal-dominant mutation in ANO5 gene associated with gnathodiaphyseal dysplasia and muscle dystrophies.Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.Functional reconstitution of a chloride channel bares its soul.Anoctamin 1 mediates thermal pain as a heat sensor.MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression.Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome.Ion channels involved in cell volume regulation: effects on migration, proliferation, and programmed cell death in non adherent EAT cells and adherent ELA cells.Primary and secondary dystonic syndromes: an update.The genetics of dystonia: new twists in an old tale.Functional swapping between transmembrane proteins TMEM16A and TMEM16F.
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Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Physiological roles and diseas ...... re they all chloride channels?
@en
Physiological roles and diseas ...... re they all chloride channels?
@nl
type
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Physiological roles and diseas ...... re they all chloride channels?
@en
Physiological roles and diseas ...... re they all chloride channels?
@nl
prefLabel
Physiological roles and diseas ...... re they all chloride channels?
@en
Physiological roles and diseas ...... re they all chloride channels?
@nl
P2860
P356
P1476
Physiological roles and diseas ...... re they all chloride channels?
@en
P2093
Charity Duran
H Criss Hartzell
P2860
P2888
P304
P356
10.1038/APS.2011.48
P577
2011-06-01T00:00:00Z