Cyclophosphamide-induced bladder inflammation sensitizes and enhances P2X receptor function in rat bladder sensory neurons.
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Research Findings on Overactive BladderNeural control of the lower urinary tractPotential for developing purinergic drugs for gastrointestinal diseasesUrothelial Tight Junction Barrier Dysfunction Sensitizes Bladder AfferentsOverexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function.Differential purinergic signaling in bladder sensory neurons of naïve and bladder-inflamed miceBladder sensory physiology: neuroactive compounds and receptors, sensory transducers, and target-derived growth factors as targets to improve function.Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity.Effects of stimulation of muscarinic receptors on bladder afferent nerves in the in vitro bladder-pelvic afferent nerve preparation of the rat.Crucial role of TRPC1 and TRPC4 in cystitis-induced neuronal sprouting and bladder overactivity.Role of Purinergic Signaling in Voiding Dysfunction.Local activation of cannabinoid CB₁ receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents.Differences in the expression of transient receptor potential channel V1, transient receptor potential channel A1 and mechanosensitive two pore-domain K+ channels between the lumbar splanchnic and pelvic nerve innervations of mouse urinary bladder aColitis decreases mechanosensitive K2P channel expression and function in mouse colon sensory neuronsVisceral pain: the neurophysiological mechanismMetabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception.Afferent nerve regulation of bladder function in health and disease.18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulationModulation of bladder function by luminal adenosine turnover and A1 receptor activation.Increased urothelial paracellular transport promotes cystitis.Nitric oxide modulates bladder afferent nerve activity in the in vitro urinary bladder-pelvic nerve preparation from rats with cyclophosphamide induced cystitis.ATP release from the human ureter on distension and P2X(3) receptor expression on suburothelial sensory nerves.Cyclophosphamide-induced cystitis reduces ASIC channel but enhances TRPV1 receptor function in rat bladder sensory neurons.Role of interleukins, IGF and stem cells in BPHPurinergic mechanosensory transduction and visceral pain.Purinergic signalling in the urinary tract in health and disease.Potential Future Pharmacological Treatment of Bladder Dysfunction.Altered expression of P2X3 in vagal and spinal afferents following esophagitis in rats.Detection of intracellular bacteria in exfoliated urothelial cells from women with urge incontinence.Inhibition of nitric oxide synthase prevents muscarinic and purinergic functional changes and development of cyclophosphamide-induced cystitis in the rat.Pannexin 1 channels mediate the release of ATP into the lumen of the rat urinary bladder.Identification of bladder and colon afferents in the nodose ganglia of male rats.The function of P2X3 receptor and NK1 receptor antagonists on cyclophosphamide-induced cystitis in rats.Mechanotransduction and chemosensitivity of two major classes of bladder afferents with endings in the vicinity to the urothelium.The role of C-fibers in the development of chronic psychological stress induced enhanced bladder sensations and nociceptive responses: A multidisciplinary approach to the study of urologic chronic pelvic pain syndrome (MAPP) research network study.Hesperidin protects against cyclophosphamide-induced hepatotoxicity by upregulation of PPARγ and abrogation of oxidative stress and inflammation.Cyclophosphamide-induced alterations of the micturition reflex in a novel in situ urinary bladder model in the anesthetized rat.Pirt reduces bladder overactivity by inhibiting purinergic receptor P2X3.Inhibitory Effects of the Standardized Extract of Phyllanthus amarus on Cellular and Humoral Immune Responses in Balb/C Mice.Role of neurogenic inflammation in local communication in the visceral mucosa.
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Cyclophosphamide-induced bladder inflammation sensitizes and enhances P2X receptor function in rat bladder sensory neurons.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 October 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@en
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@nl
type
label
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@en
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@nl
prefLabel
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@en
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@nl
P2093
P2860
P356
P1476
Cyclophosphamide-induced bladd ...... n rat bladder sensory neurons.
@en
P2093
G F Gebhart
Kenneth Lamb
Klaus Bielefeldt
Michael Cohen
P2860
P356
10.1152/JN.00211.2007
P407
P577
2007-10-24T00:00:00Z