Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.
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The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogenThe Anti-inflammatory Role of Endometase/Matrilysin-2 in Human Prostate Cancer CellsMMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglinGene expression profiling of the tumor microenvironment during breast cancer progression.Role of multi-hnRNP nuclear complex in regulation of tumor suppressor ANXA7 in prostate cancer cells.Overexpression of nuclear protein kinase CK2 α catalytic subunit (CK2α) as a poor prognosticator in human colorectal cancer.Diverse functions for the semaphorin receptor PlexinD1 in development and disease.Potential relation of aberrant proteolysis of human protein tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects.Protein kinase CK2 in health and disease: CK2: a key player in cancer biologyMembrane type-1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancerThe Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity.MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function.Identification of a biomarker panel for colorectal cancer diagnosis.Increased expression of protein kinase CK2α correlates with poor patient prognosis in epithelial ovarian cancer.Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7)RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.Effect of MT1-MMP deficiency and overexpression in corneal keratocytes on vascular endothelial cell migration and proliferationBiochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cellsNew Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies.Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity.Prostaglandin transporter, SLCO2A1, mediates the invasion and apoptosis of lung cancer cells via PI3K/AKT/mTOR pathway.In vivo and in vitro effect of hepatocarcinoma lymph node metastasis by upregulation of Annexin A7 and relevant mechanisms.Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes.Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.More precise prediction in Chinese patients with penile squamous cell carcinoma: protein kinase CK2α catalytic subunit (CK2α) as a poor prognosticator.The human cell surfaceome of breast tumors.Unbalanced expression of CK2 kinase subunits is sufficient to drive epithelial-to-mesenchymal transition by Snail1 induction.Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma.Gene expression signatures of angiocidin and darapladib treatment connect to therapy options in cervical cancer.H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression.Harnessing membrane trafficking to promote cancer spreading and invasion: The case of RAB2A.STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas
P2860
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P2860
Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2008
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@en
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@nl
type
label
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@en
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@nl
prefLabel
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@en
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@nl
P2093
P2860
P1433
P1476
Molecular signature of MT1-MMP ...... versal gene network in cancer.
@en
P2093
Alex Y Strongin
Alexei Y Savinov
Dmitri V Rozanov
Roy Williams
Stan Krajewski
Vladislav S Golubkov
P2860
P304
P356
10.1158/0008-5472.CAN-07-6458
P407
P577
2008-06-01T00:00:00Z