Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance
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Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer MedicineComplex correlations: replication timing and mutational landscapes during cancer and genome evolutionDose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer PatientsDetecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callersQuantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapyInconsistency and features of single nucleotide variants detected in whole exome sequencing versus transcriptome sequencing: A case study in lung cancer.Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells.Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbationsAdvances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomesGenomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumorsUnraveling tumor grading and genomic landscape in lung neuroendocrine tumors.Next generation sequencing: implications in personalized medicine and pharmacogenomics.Understanding Mechanisms of Resistance in the Epithelial Growth Factor Receptor in Non-Small Cell Lung Cancer and the Role of Biopsy at Progression.HNSCC cells resistant to EGFR pathway inhibitors are hypermutated and sensitive to DNA damaging substances.Perturbations in the Replication Program Contribute to Genomic Instability in Cancer.Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response.Overall survival in EGFR mutated non-small-cell lung cancer patients treated with afatinib after EGFR TKI and resistant mechanisms upon disease progression.CNVannotator: a comprehensive annotation server for copy number variation in the human genome.Stress-induced cellular adaptive strategies: ancient evolutionarily conserved programs as new anticancer therapeutic targets.Breast Cancer Risk Associated with Genotype Polymorphisms of the Aurora Kinase a Gene (AURKA): a Case-Control Study in a High Altitude Ecuadorian Mestizo Population.
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Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Next-generation sequencing of ...... ssociated with drug resistance
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Next-generation sequencing of ...... sociated with drug resistance.
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type
label
Next-generation sequencing of ...... ssociated with drug resistance
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Next-generation sequencing of ...... sociated with drug resistance.
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Next-generation sequencing of ...... ssociated with drug resistance
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Next-generation sequencing of ...... sociated with drug resistance.
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Next-generation sequencing of ...... ssociated with drug resistance
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Catherine B Meador
Franziska Michor
Hailing Jin
Junfeng Xia
Kadoaki Ohashi
Kimberly B Dahlman
Peilin Jia
Zhongming Zhao
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P304
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10.1101/GR.152322.112
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2013-06-03T00:00:00Z