Antipsychotic drug mechanisms: links between therapeutic effects, metabolic side effects and the insulin signaling pathway.
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Obesity and Its Potential Effects on Antidepressant Treatment Outcomes in Patients with Depressive Disorders: A Literature ReviewAntipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotectionAssociation of the PPAR-γ Gene with Altered Glucose Levels and Psychosis Profile in Schizophrenia Patients Exposed to Antipsychotics.Vitamin D insufficiency and schizophrenia risk: evaluation of hyperprolinemia as a mediator of association.Antipsychotic-induced gene regulation in multiple brain regions.Effects of sports participation on psychiatric symptoms and brain activations during sports observation in schizophreniaThe 'Holy Grail' and 'Poisoned Chalice' Effects of Antipsychotics on Oxidative Stress in Schizophrenia: Can 'Hormesis' Explain this Paradox?Crosstalk between metabolic and neuropsychiatric disordersDopamine synthesis and D3 receptor activation in pancreatic β-cells regulates insulin secretion and intracellular [Ca(2+)] oscillations.A Longitudinal Study of Relation between Side-effects and Clinical Improvement in Schizophrenia: Is There a Neuro-metabolic Threshold for Second Generation Antipsychotics?Minireview: Dopaminergic regulation of insulin secretion from the pancreatic islet.Metabolic syndrome in schizophrenia: theoretical, clinical and translational perspectives.Drug discovery based on genetic and metabolic findings in schizophrenia.Are medical comorbid conditions of bipolar disorder due to immune dysfunction?Steviol glycosides modulate glucose transport in different cell types.Clozapine as a Model for Antipsychotic Development.Clozapine promotes glycolysis and myelin lipid synthesis in cultured oligodendrocytes.Clozapine interaction with phosphatidyl inositol 3-kinase (PI3K)/insulin-signaling pathway in Caenorhabditis elegans.Clozapine: a distinct, poorly understood and under-used molecule.In male rats, the ability of central insulin to suppress glucose production is impaired by olanzapine, whereas glucose uptake is left intact.Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways.Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder.Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis.In male rats, the ability of central insulin to suppress glucose production is impaired by olanzapine, whereas glucose uptake is left intact.Olanzapine-induced early cardiovascular effects are mediated by the biological clock and prevented by melatonin.Involvement of histamine receptors in the atypical antipsychotic profile of clozapine: a reassessment in vitro and in vivo.The Complex Relationship between Antipsychotic-Induced Weight Gain and Therapeutic Benefits: A Systematic Review and Implications for Treatment.Melatonin attenuates antipsychotic metabolic effects: an eight-week randomized, double-blind, parallel-group, placebo-controlled clinical trial.Hyperprolactinemia and insulin resistance in drug naive patients with early onset first episode psychosis
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Antipsychotic drug mechanisms: links between therapeutic effects, metabolic side effects and the insulin signaling pathway.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 15 April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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type
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Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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Antipsychotic drug mechanisms: ...... the insulin signaling pathway.
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J A Javitch
J A Lieberman
R R Girgis
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P2888
P304
P356
10.1038/MP.2008.40
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P577
2008-04-15T00:00:00Z