Mesothelin overexpression promotes mesothelioma cell invasion and MMP-9 secretion in an orthotopic mouse model and in epithelioid pleural mesothelioma patients. - Wikidata - wikimedia - TriplyDB

Mesothelin overexpression promotes mesothelioma cell invasion and MMP-9 secretion in an orthotopic mouse model and in epithelioid pleural mesothelioma patients.

Mesothelin overexpression promotes mesothelioma cell invasion and MMP-9 secretion in an orthotopic mouse model and in epithelioid pleural mesothelioma patients.

http://www.wikidata.org/entity/Q37139387

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Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes New Strategies for the Treatment of Solid Tumors with CAR-T Cells Clinical impacts of mesothelin expression in gastrointestinal carcinomas Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors Current issues in malignant pleural mesothelioma evaluation and management Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells Surgical immune interventions for solid malignancies.Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes.Re-adapting T cells for cancer therapy: from mouse models to clinical trials.Comprehensive immunohistochemical study of mesothelin (MSLN) using different monoclonal antibodies 5B2 and MN-1 in 1562 tumors with evaluation of its prognostic value in malignant pleural mesothelioma.Mesothelin Immunotherapy for Cancer: Ready for Prime Time?Novel immunotherapy clinical trials in malignant pleural mesothelioma.Immunotherapy for malignant pleural mesothelioma: current status and future directions.Diagnostic and prognostic biomarkers for malignant mesothelioma: an update.Serum IGFBP2 and MSLN as diagnostic and prognostic biomarkers for pancreatic cancer.Malignant pleural mesothelioma: an update on diagnosis and treatment options.Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials.Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity.A novel PET imaging using ⁶⁴Cu-labeled monoclonal antibody against mesothelin commonly expressed on cancer cells The tumoral and stromal immune microenvironment in malignant pleural mesothelioma: A comprehensive analysis reveals prognostic immune markers Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer.Immunotherapy for non-small cell lung cancer: current concepts and clinical trials.Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation.Mesothelin-targeted immunotherapies for malignant pleural mesothelioma.Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.Do mesothelin/MUC16 interactions facilitate adenocarcinoma metastases to intracranial meningiomas?Mesothelin overexpression is a marker of tumor aggressiveness and is associated with reduced recurrence-free and overall survival in early-stage lung adenocarcinoma.Chimeric Antigen Receptor (CAR) T Cell Therapy for Malignant Pleural Mesothelioma (MPM).Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing.Biomarkers and prognostic factors for malignant pleural mesothelioma.Mesothelin as a target for chimeric antigen receptor-modified T cells as anticancer therapy.C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma.CAR T-cell therapy for pancreatic cancer.Mesothelin promotes invasion and metastasis in breast cancer cells.CAR T-cell therapy for lung cancer and malignant pleural mesothelioma.Prognostic significance of soluble mesothelin in malignant pleural mesothelioma: a meta-analysis.Mesothelin Expression in Gastric Adenocarcinoma and Its Relation to Clinical Outcomes

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Mesothelin overexpression promotes mesothelioma cell invasion and MMP-9 secretion in an orthotopic mouse model and in epithelioid pleural mesothelioma patients.

http://www.wikidata.org/entity/Q37139387

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article científic

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articolo scientifico

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bilimsel makale

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scientific article published on 27 February 2012

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vedecký článok

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vetenskaplig artikel

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vědecký článek

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name

Mesothelin overexpression prom ...... pleural mesothelioma patients.

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Mesothelin overexpression prom ...... pleural mesothelioma patients.

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Mesothelin overexpression prom ...... pleural mesothelioma patients.

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Mesothelin overexpression prom ...... pleural mesothelioma patients.

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Mesothelin overexpression prom ...... pleural mesothelioma patients.

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Mesothelin overexpression prom ...... pleural mesothelioma patients.

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Clinical Cancer Research

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Mesothelin overexpression prom ...... pleural mesothelioma patients

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Adam J Bograd

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Camelia Sima

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Christos Colovos

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Elliot L Servais

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Jun-ichi Nitadori

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Luis Rodriguez

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Michel Sadelain

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Prasad S Adusumilli

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P2860

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Ranpirnase Interferes with NF-κB Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft Growth

Circulating mesothelin protein and cellular antimesothelin immunity in patients with pancreatic cancer

Mesothelin targeted cancer immunotherapy

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

Stromelysin-1 and mesothelin are differentially regulated by Wnt-5a and Wnt-1 in C57mg mouse mammary epithelial cells

Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops

Mesothelin inhibits paclitaxel-induced apoptosis through the PI3K pathway

Soluble mesothelin-related peptide level elevation in mesothelioma serum and pleural effusions

Mesothelin promotes anchorage-independent growth and prevents anoikis via extracellular signal-regulated kinase signaling pathway in human breast cancer cells

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2478-2489

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10.1158/1078-0432.CCR-11-2614

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9

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Valerie W Rusch

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22371455

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