Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis
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TularemiaHost-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.Cellular and humoral immunity are synergistic in protection against types A and B Francisella tularensis.The francisella tularensis proteome and its recognition by antibodies.Francisella tularensis LVS surface and membrane proteins as targets of effective post-exposure immunization for tularemia.Francisella tularensis-specific T-cell clones are human leukocyte antigen class II restricted, secrete interleukin-2 and gamma interferon, and induce immunoglobulin production.Cell-mediated and humoral immune responses after vaccination of human volunteers with the live vaccine strain of Francisella tularensis.Cytokine expression in the liver during the early phase of murine tularemia.Characterization of the nucleotide sequence of the groE operon encoding heat shock proteins chaperone-60 and -10 of Francisella tularensis and determination of the T-cell response to the proteins in individuals vaccinated with F. tularensisIdentification of proteins of Francisella tularensis induced during growth in macrophages and cloning of the gene encoding a prominently induced 23-kilodalton proteinCharacterization of Francisella tularensis outer membrane proteins.Protective immunity against tularemia provided by an adenovirus-vectored vaccine expressing Tul4 of Francisella tularensis.Humoral and cell-mediated immunity in mice to a 17-kilodalton lipoprotein of Francisella tularensis expressed by Salmonella typhimuriumDevelopment of Francisella tularensis antigen responses measured as T-lymphocyte proliferation and cytokine production (tumor necrosis factor alpha, gamma interferon, and interleukin-2 and -4) during human tularemia.The T-cell-stimulating 17-kilodalton protein of Francisella tularensis LVS is a lipoproteinDiversity of Francisella tularensis antigens recognized by human T lymphocytes.A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes.TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis.Cell-mediated and humoral immune responses induced by scarification vaccination of human volunteers with a new lot of the live vaccine strain of Francisella tularensis.Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development.Monocyte/macrophage inflammatory response pathways to combat Francisella infection: possible therapeutic targets?Method for the isolation of Francisella tularensis outer membranes.Agglutinins and antibodies to Francisella tularensis outer membrane antigens in the early diagnosis of disease during an outbreak of tularemia.Competitive enzyme immunoassay for antibodies to a 43,000-molecular-weight Francisella tularensis outer membrane protein for the diagnosis of tularemia.Several membrane polypeptides of the live vaccine strain Francisella tularensis LVS stimulate T cells from naturally infected individuals.
P2860
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P2860
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 1987
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis
@en
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis.
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type
label
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis
@en
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis.
@nl
prefLabel
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis
@en
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis.
@nl
P2093
P2860
P1476
Immunospecific T-lymphocyte stimulation by membrane proteins from Francisella tularensis
@en
P2093
Sandström G
Wolf-Watz H
P2860
P304
P407
P577
1987-04-01T00:00:00Z