Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse
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Transformation of Follicular Lymphoma to a High-Grade B-Cell Lymphoma With MYC and BCL2 Translocations and Overlapping Features of Burkitt Lymphoma and Acute Lymphoblastic Leukemia: A Case Report and Literature Review.Immunohistochemical analysis indicates that the anatomical location of B-cell non-Hodgkin's lymphoma is determined by differentially expressed chemokine receptors, sphingosine-1-phosphate receptors and integrinsDC-SIGN-expressing macrophages trigger activation of mannosylated IgM B-cell receptor in follicular lymphoma.Next generation sequencing of the clonal IGH rearrangement detects ongoing mutations and interfollicular trafficking in in situ follicular neoplasia.The molecular pathogenesis of B-cell non-Hodgkin lymphoma.Oncogenic events rather than antigen selection pressure may be the main driving forces for relapse in diffuse large B-cell lymphomas.Origin and migration of follicular lymphoma cells.
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Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Somatic hypermutation analysis ...... isease progression and relapse
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Somatic hypermutation analysis ...... sease progression and relapse.
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type
label
Somatic hypermutation analysis ...... isease progression and relapse
@en
Somatic hypermutation analysis ...... sease progression and relapse.
@nl
prefLabel
Somatic hypermutation analysis ...... isease progression and relapse
@en
Somatic hypermutation analysis ...... sease progression and relapse.
@nl
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P2860
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Somatic hypermutation analysis ...... isease progression and relapse
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Andreas Rosenwald
Christian Meyer zum Bueschenfelde
German Ott
Marcus Kremer
Martin Wartenberg
Peter Vasil
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P304
P356
10.3324/HAEMATOL.2012.074252
P50
P577
2013-04-12T00:00:00Z