Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.
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Role of T cell-nuclear factor κB in transplantationPharmGKB summary: very important pharmacogene information for the epidermal growth factor receptorMyc suppression of Nfkb2 accelerates lymphomagenesis.Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.The noncanonical NF-κB pathway.Inhibition of pluripotent stem cell-derived teratoma formation by small moleculesNF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.NF-κB and cancer: a paradigm of Yin-Yang.Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunityNF-κB–inducing kinase plays an essential T cell–intrinsic role in graft-versus-host disease and lethal autoimmunity in miceTNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100).NF-κB signaling mediates homeostatic maturation of new T cells.The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells.Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients.p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity.Uncaria tomentosa (Willd. ex Schult.) DC (Rubiaceae) Sensitizes THP-1 Cells to Radiation-induced Cell Death.Tumor-suppressor NFκB2 p100 interacts with ERK2 and stabilizes PTEN mRNA via inhibition of miR-494Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.
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Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 February 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Constitutive production of NF- ...... by repressing Bim expression.
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Constitutive production of NF- ...... by repressing Bim expression.
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type
label
Constitutive production of NF- ...... by repressing Bim expression.
@en
Constitutive production of NF- ...... by repressing Bim expression.
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prefLabel
Constitutive production of NF- ...... by repressing Bim expression.
@en
Constitutive production of NF- ...... by repressing Bim expression.
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P2093
P2860
P356
P1476
Constitutive production of NF- ...... e by repressing Bim expression
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P2093
Han-Fei Ding
Liqun Yang
P2860
P304
10698-10706
P356
10.1074/JBC.M800806200
P407
P577
2008-02-15T00:00:00Z