Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease.
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Therapeutic strategies for the clinical blockade of IL-6/gp130 signalingExpression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in miceMicroRNAs as potential signatures of environmental exposure or effect: a systematic reviewApi6/AIM/Spα/CD5L overexpression in alveolar type II epithelial cells induces spontaneous lung adenocarcinomaStat3 downstream gene product chitinase 3-like 1 is a potential biomarker of inflammation-induced lung cancer in multiple mouse lung tumor models and humans.Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke.Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation.Large-scale, ion-current-based proteomics investigation of bronchoalveolar lavage fluid in chronic obstructive pulmonary disease patientsNontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer.Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal(-/-) miceOverexpression of dominant negative peroxisome proliferator-activated receptor-γ (PPARγ) in alveolar type II epithelial cells causes inflammation and T-cell suppression in the lung.Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in miceSignal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis.Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.Significance of CXCR4, phosphorylated STAT3 and VEGF-A expression in resected non-small cell lung cancer.Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout MiceIL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.STAT3 modulates cigarette smoke-induced inflammation and protease expressionMatrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis.Common pathogenic mechanisms and pathways in the development of COPD and lung cancer.How the genetics of lung cancer may overlap with COPD.New anti-inflammatory targets for chronic obstructive pulmonary disease.Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.Lung Epithelial Cell-Specific Expression of Human Lysosomal Acid Lipase Ameliorates Lung Inflammation and Tumor Metastasis in Lipa(-/-) MiceGprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor.MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease.Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice
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P2860
Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 09 July 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
@da
vědecký článek
@cs
name
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
@en
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
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type
label
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
@en
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
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prefLabel
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
@en
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
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P2093
P2860
P1433
P1476
Stat3 downstream genes serve a ...... obstructive pulmonary disease.
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P2093
Jennifer Roberts
John N Eble
Marjorie Albrecht
Oscar W Cummings
P2860
P304
P356
10.1016/J.LUNGCAN.2008.05.025
P577
2008-07-09T00:00:00Z