Protein kinase a mediates activity-dependent Kv4.2 channel trafficking
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Functional mapping of protein kinase A reveals its importance in adult Schistosoma mansoni motor activityDPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neuronsMembrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel functionAnalysis and functional implications of phosphorylation of neuronal voltage-gated potassium channels.Molecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationKChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation.Downregulation of Kv4.2 channels mediated by NR2B-containing NMDA receptors in cultured hippocampal neuronsDendritic ion channel trafficking and plasticity.Mining recent brain proteomic databases for ion channel phosphosite nuggets.AKAP79/150 impacts intrinsic excitability of hippocampal neurons through phospho-regulation of A-type K+ channel trafficking.Differential cycling rates of Kv4.2 channels in proximal and distal dendrites of hippocampal CA1 pyramidal neurons.Activity-dependent phosphorylation of neuronal Kv2.1 potassium channels by CDK5.The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels.Unique somato-dendritic distribution pattern of Kv4.2 channels on hippocampal CA1 pyramidal cellsConvergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide.Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic β-adrenergic signaling.Learning-related postburst afterhyperpolarization reduction in CA1 pyramidal neurons is mediated by protein kinase AAntibody-guided photoablation of voltage-gated potassium currentsThe role of calsenilin/DREAM/KChIP3 in contextual fear conditioningActivation of high and low affinity dopamine receptors generates a closed loop that maintains a conductance ratio and its activity correlate.Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits.Excitatory roles of protein kinase C in striatal cholinergic interneurons.Inhibition of glutamate transporters couples to Kv4.2 dephosphorylation through activation of extrasynaptic NMDA receptorsChronic Ca2+ influx through voltage-dependent Ca2+ channels enhance delayed rectifier K+ currents via activating Src family tyrosine kinase in rat hippocampal neurons.Neuronal homeostasis: time for a change?IA channels: diverse regulatory mechanisms.Roles of somatic A-type K(+) channels in the synaptic plasticity of hippocampal neurons.The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms.Agonist- and Ca2+-dependent desensitization of TRPV1 channel targets the receptor to lysosomes for degradation.Corticosterone rapidly increases thorns of CA3 neurons via synaptic/extranuclear glucocorticoid receptor in rat hippocampus.Activation of κ opioid receptors increases intrinsic excitability of dentate gyrus granule cells.Potential for therapeutic targeting of AKAP signaling complexes in nervous system disorders.Activity-dependent downregulation of D-type K+ channel subunit Kv1.2 in rat hippocampal CA3 pyramidal neurons.Somatodendritic surface expression of epitope-tagged and KChIP binding-deficient Kv4.2 channels in hippocampal neurons.Activation of ryanodine receptors is required for PKA-mediated downregulation of A-type K+ channels in rat hippocampal neurons.Cyclic AMP Signaling Control of Action Potential Firing Rate and Molecular Circadian Pacemaking in the Suprachiasmatic Nucleus
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Protein kinase a mediates activity-dependent Kv4.2 channel trafficking
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on July 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking
@en
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.
@nl
type
label
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking
@en
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.
@nl
prefLabel
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking
@en
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.
@nl
P2093
P2860
P1476
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking
@en
P2093
Andrew M Wikenheiser
Dax A Hoffman
Michael S Sidorov
Rebecca S Hammond
P2860
P304
P356
10.1523/JNEUROSCI.1951-08.2008
P407
P577
2008-07-01T00:00:00Z