Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities
about
Sex-linked barring in chickens is controlled by the CDKN2A /B tumour suppressor locus.The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent mannerMimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts.The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis.TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome AmplificationA conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction.The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2ANMI mediates transcription-independent ARF regulation in response to cellular stressesDifferential effects on ARF stability by normal versus oncogenic levels of c-Myc expression.ARF inhibits the growth and malignant progression of non-small-cell lung carcinoma.PKC Dependent p14ARF Phosphorylation on Threonine 8 Drives Cell Proliferation.
P2860
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P2860
Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 27 January 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Residues in the alternative re ...... and p53-independent activities
@en
Residues in the alternative re ...... nd p53-independent activities.
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type
label
Residues in the alternative re ...... and p53-independent activities
@en
Residues in the alternative re ...... nd p53-independent activities.
@nl
prefLabel
Residues in the alternative re ...... and p53-independent activities
@en
Residues in the alternative re ...... nd p53-independent activities.
@nl
P2093
P2860
P1476
Residues in the alternative re ...... and p53-independent activities
@en
P2093
Alain Kitzis
Amel Dudakovic
Anne di Tommaso
Jussara Hagen
Veronique Ladeveze
Viviane Muniz
P2860
P304
P356
10.1016/J.YEXCR.2009.01.010
P407
P577
2009-01-27T00:00:00Z