Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.
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Complexity of vitamin E metabolismChallenges in applying chemometrics to LC-MS-based global metabolite profile data.Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challengeAnalysis of multiple metabolites of tocopherols and tocotrienols in mice and humans.α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymesNovel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomicsCytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized miceTowards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach.CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid.Mechanisms for the prevention of vitamin E excessOptimization of the enzymatic hydrolysis and analysis of plasma conjugated gamma-CEHC and sulfated long-chain carboxychromanols, metabolites of vitamin ESerum Metabolomic Response to Long-Term Supplementation with all-rac-α-Tocopheryl Acetate in a Randomized Controlled Trial.Nuclear receptor PXR, transcriptional circuits and metabolic relevance.A rough guide to metabolite identification using high resolution liquid chromatography mass spectrometry in metabolomic profiling in metazoansIdentification of urinary biomarkers of colon inflammation in IL10-/- mice using Short-Column LCMS metabolomicsA metabolomic investigation of the effects of vitamin E supplementation in humans.Meclizine Prevents Ovariectomy-Induced Bone Loss and Inhibits Osteoclastogenesis Partially by Upregulating PXR.Scientific Opinion on Dietary Reference Values for vitamin E as α-tocopherol
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P2860
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@en
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@nl
type
label
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@en
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@nl
prefLabel
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@en
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@nl
P2093
P2860
P1476
Metabolomics reveals a novel v ...... etabolism upon PXR activation.
@en
P2093
Dong Wook Kang
Frank J Gonzalez
Jeffrey R Idle
Joo-Youn Cho
Kristopher W Krausz
Sung-Hoon Ahn
Xiaochao Ma
P2860
P304
P356
10.1194/JLR.M800647-JLR200
P50
P577
2009-01-13T00:00:00Z