Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3
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MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cellsGlycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapyCell migration in paediatric glioma; characterisation and potential therapeutic targeting.GSK3beta regulates differentiation and growth arrest in glioblastomaTherapeutic strategies for inhibiting invasion in glioblastoma.Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion.GSK3beta: role in therapeutic landscape and development of modulators.Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models.Wnt activation promotes neuronal differentiation of glioblastomaExperimental approaches for the treatment of malignant gliomas.Indirubins decrease glioma invasion by blocking migratory phenotypes in both the tumor and stromal endothelial cell compartmentsGlycogen synthase kinase 3β dictates podocyte motility and focal adhesion turnover by modulating paxillin activity: implications for the protective effect of low-dose lithium in podocytopathy.The impact of phenotypic switching on glioblastoma growth and invasion.Lithium inhibits tumorigenic potential of PDA cells through targeting hedgehog-GLI signaling pathway.Morphological analysis of CDC2 and glycogen synthase kinase 3β phosphorylation as markers of g2 → m transition in gliomaPolarized regulation of glycogen synthase kinase-3β is important for glioma cell invasion.GSK3β overexpression indicates poor prognosis and its inhibition reduces cell proliferation and survival of non-small cell lung cancer cellsChondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy.Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3β/β-catenin signaling pathwayFunctions of GSK-3 Signaling in Development of the Nervous System.Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo.Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone.The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells.Combined application of arsenic trioxide and lithium chloride augments viability reduction and apoptosis induction in human rhabdomyosarcoma cell lines.miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal.Lithium inhibits tumor lymphangiogenesis and metastasis through the inhibition of TGFBIp expression in cancer cellsCombination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cellsTherapeutic targets in malignant glioblastoma microenvironmentGenetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma.Wnt/β-catenin signaling pathway inhibits the proliferation and apoptosis of U87 glioma cells via different mechanisms.Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.A Metabolic Inhibitory Cocktail for Grave Cancers: Metformin, Pioglitazone and Lithium Combination in Treatment of Pancreatic Cancer and Glioblastoma Multiforme.Lithium chloride suppresses colorectal cancer cell survival and proliferation through ROS/GSK-3β/NF-κB signaling pathwayLithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β.Sorafenib and lithium chloride combination treatment shows promising synergistic effects in human glioblastoma multiforme cells in vitro but midkine is not implicated.A potential strategy for high-grade gliomas: combination treatment with lithium chloride and BmK CT.Differential display RT-PCR reveals genes associated with lithium-induced neuritogenesis in SK-N-MC cells.
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P2860
Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3
@en
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3.
@nl
type
label
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3
@en
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3.
@nl
prefLabel
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3
@en
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3.
@nl
P2093
P2860
P1433
P1476
Lithium inhibits invasion of g ...... of glycogen synthase kinase-3
@en
P2093
Andrew M Stein
E Antonio Chiocca
Herbert B Newton
Jakub Godlewski
Jennifer L Cutter
Leonard M Sander
Masayuki Nita
Michael E Berens
Michal O Nowicki
Nina Dmitrieva
P2860
P304
P356
10.1215/15228517-2008-041
P577
2008-08-20T00:00:00Z