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An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cellsTumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitorsNanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphomaTaspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosisPLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cellsAntiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinomaThe Contrived Mutant p53 Oncogene - Beyond Loss of FunctionsOncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer CellsAmplification of Cellular Oncogenes in Solid TumorsMetabolic reprogramming: the emerging concept and associated therapeutic strategiesUsing large-scale genomics data to identify driver mutations in lung cancer: methods and challengesNext-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneityResistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategiesMYC activation is a hallmark of cancer initiation and maintenanceSignaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junctionTargeting CD19 in B-cell lymphoma: emerging role of SAR3419Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like CellsSystems biology approaches for advancing the discovery of effective drug combinationsEvaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study.Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling.Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cellsNeratinib in HER-2-positive breast cancer: results to date and clinical usefulnessTargeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentMechanisms of cancer cell killing by the adenovirus E4orf4 proteinMolecular pathogenesis of peripheral neuroblastic tumorsStratification and therapeutic potential of PML in metastatic breast cancerEfficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapyCancer missense mutations alter binding properties of proteins and their interaction networksComprehensive suppression of all apoptosis-induced proliferation pathways as a proposed approach to colorectal cancer prevention and therapyBRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implicationsThe E6AP binding pocket of the HPV16 E6 oncoprotein provides a docking site for a small inhibitory peptide unrelated to E6AP, indicating druggability of E6The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 PathwaysOpen pipelines for integrated tumor genome profiles reveal differences between pancreatic cancer tumors and cell linesCancer in light of experimental evolutionAdvances in chemical carcinogenesis: a historical review and prospectivePrinciples of cancer therapy: oncogene and non-oncogene addictionTargeting MYC dependence in cancer by inhibiting BET bromodomainsPostal survey of physicians and laboratories: practices and perceptions of molecular oncology testingDiacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.Molecular genesis of non-muscle-invasive urothelial carcinoma (NMIUC)
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
gotara zanistî
@ku-latn
scientific article published on May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
name
Oncogene addiction.
@en
Oncogene addiction.
@nl
type
label
Oncogene addiction.
@en
Oncogene addiction.
@nl
prefLabel
Oncogene addiction.
@en
Oncogene addiction.
@nl
P1433
P1476
Oncogene addiction.
@en
P2093
Andrew Joe
I Bernard Weinstein
P304
3077-80; discussion 3080
P356
10.1158/0008-5472.CAN-07-3293
P407
P577
2008-05-01T00:00:00Z